A thorough and comprehensive knowledge of the evolutionary pattern in the thermal-hydraulic-mechanical-chemical (THMC) behavior of cement-stabilized clay is essential for a more reasonable design of improved clay in practical engineering. Sensitive marine clays with low strength, reinforced by various cement contents (0%, 6%, and 12%), were produced as samples to study the evolutionary pattern of the THMC behavior of reinforced clays. Samples with designed curing times (1, 3, 7, 28, and 90 days) will be trimmed to the appropriate size and utilized in a series of mechanical tests. Furthermore, the other portion of the samples, which is pre-installed with sensors, is used to monitor the development in internal temperature, volumetric water content, suction, and electrical conductivity for 90 days. The results showed that the content of cement and curing time have a significant influence on the THMC behavior of reinforced clay. Meanwhile, the results indicate a strong coupling of the THMC behavior of clays reinforced by cement. The results will be of critical assistance in gaining advanced knowledge into the evolutionary pattern in the THMC behavior of reinforced clays as well as making a contribution to optimizing the stability, cost-effectiveness, and durability of the design of reinforced clays.