Numerical analysis of coronary artery bypass grafts: An over view

Owida, Amal; Do, Hung; Morsi, Yos S.

doi:10.1016/j.cmpb.2011.12.005

Cited by 76 publications

(47 citation statements)

References 72 publications

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“…Over the years, there have been presented numerical, experimental and clinical studies that show the efficiency of different types of grafts (e.g. straight, S-type, helical) used in by-pass surgery [5,[8][9][10][11]. As presented in the literature, graft patency increases in case of helical grafts [4,5].…”

Section: Introductionmentioning

confidence: 93%

Fluid dynamics in helical geometries with applications for by-pass grafts

Totorean

Bernad

Susan-Resiga

2016

Applied Mathematics and Computation

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Section: Introductionmentioning

confidence: 93%

Fluid dynamics in helical geometries with applications for by-pass grafts

Totorean

Bernad

Susan-Resiga

2016

Applied Mathematics and Computation

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“…1,2 These factors include disturbed blood flow patterns, low and oscillating wall shear stress (WSS), sufficiently high WSS, large spatial WSS gradients, and the stagnation of blood cells. 3, 4 Grafts to the coronary artery commonly involve end-toside (ETS) anastomoses. It has been shown that, after such procedures, IH develops predominantly at the toe and heel of such anastomoses and on the arterial floor across the junction, where the disturbance of flow patterns and other hemodynamic factors have reportedly been observed.…”

Section: Methodsmentioning

confidence: 99%

Analysis of Computational Fluid Dynamics and Particle Image Velocimetry Models of Distal-End Side-to-Side and End-to-Side Anastomoses for Coronary Artery Bypass Grafting in a Pulsatile Flow

Shintani

Iino

Yamamoto

et al. 2018

Circ J

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deSTS anastomosis has not yet been reported. This study is designed to investigate flow fields in deSTS-simulated left internal thoracic artery (LITA)-left anterior descending artery (LAD) anastomoses, examine differences between deSTS and ETS anastomoses in flow fields using computational fluid dynamics (CFD), and validate the findings via particle image velocimetry (PIV). MethodsThe internal thoracic artery (ITA) is a proven excellent conduit to use when performing CABG. ETS or deSTS anastomoses are usually used to connect the distal end of the ITA-LAD anastomoses. Therefore, in our model, it was assumed that the anastomoses were to the distal end of the LITA-LAD anastomoses.A series of separate studies were performed. First, steady and pulsatile flows were investigated in an actual size model (Model A) using CFD. Next, CFD simulations and PIV measurements of the steady flow were used to validate C oronary artery bypass grafting (CABG) has long been used to facilitate arterial revascularization. Anastomotic intimal hyperplasia (IH) is a major cause of graft failure. It has been shown that hemodynamic factors are involved in IH formation and progression. 1,2 These factors include disturbed blood flow patterns, low and oscillating wall shear stress (WSS), sufficiently high WSS, large spatial WSS gradients, and the stagnation of blood cells. 3, 4 Grafts to the coronary artery commonly involve end-toside (ETS) anastomoses. It has been shown that, after such procedures, IH develops predominantly at the toe and heel of such anastomoses and on the arterial floor across the junction, where the disturbance of flow patterns and other hemodynamic factors have reportedly been observed. 2, 5 Meanwhile, several recent studies have reported the usefulness of distal-end side-to-side (deSTS) anastomoses. 6,7 Umezu et al 8 reported that deSTS anastomoses lose less energy than ETS anastomoses. However, a detailed 3-dimensional assessment of the hemodynamic characteristics of Background: Intimal hyperplasia (IH) is a major cause of graft failure. Hemodynamic factors such as stagnation and disturbed blood flow are involved in IH formation. The aim of this study is to perform a comparative analysis of distal-end side-to-side (deSTS) and endto-side (ETS) anastomoses using computational fluid dynamics (CFD) after validating the results via particle image velocimetry (PIV).

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“…Moreover, new designs of various artificial devices to aid the functionality of the heart and main blood vessels, such as ventricular assist devices (VADs), stents and valves, have been widely proposed and implemented with various degrees of success. [12][13][14][15][16][17][18] However, research is still ongoing as there is a need to develop a rigorous synergy between advanced simulation tools and experimental diagnostic methodologies.…”

Section: Overviewmentioning

confidence: 99%

Cardiovascular haemodynamics: Advancement of numerical and experimental diagnostic tools

Morsi

Hellevik

Qiao

et al. 2015

Advances in Mechanical Engineering

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OverviewCardiovascular diseases (CVDs) are the main cause of death in developed world. After a few decades of research, the clear anatomic functional and haemodynamic interdependency of cardiovascular assemblies and the use of various simulation tools to analyse such interactions are well recognized and documented. [1][2][3][4] In line with this recent advances in computational fluid dynamics (CFD), laser diagnostics and imagining processing have introduced new methodologies to study the CVDs and the mechanisms underlying their pathology. [5][6][7][8][9][10][11] Knowledge gained from implementing these tools has led to the development of successful therapies and novel tools to characterize these clinical conditions and assist in the development of a precise, preventive and predictive treatment for CVDs. Moreover, new designs of various artificial devices to aid the functionality of the heart and main blood vessels, such as ventricular assist devices (VADs), stents and valves, have been widely proposed and implemented with various degrees of success.12-18 However, research is still ongoing as there is a need to develop a rigorous synergy between advanced simulation tools and experimental diagnostic methodologies.In this Special Issue of CVDs, a total of 12 articles were submitted of which only 5 have been accepted after rigorous reviewing. We are pleased to present such excellent work in our journal. The 5 articles include the work of Hu and Cai, who investigated the flexible deformation of the guide wire in a force feedback device of virtual cardiovascular surgery to determine the optimal length of the guide wire. The authors experimentally determined the performance of force transmission by varying the length of the guide wire and determined the optimal length of the wire that gave maximum force to the actuator. Such approach can be equally applied to optimize and enhance the dynamic performance of other catheter-type surgery instruments.Ga˚rdhagen et al. used large eddy simulation (LES) method to examine the haemodynamic of the coartation of the aorta (CoA) and post-stenosis dilatation. In this study, different haemodynamic parameters associated with the vascular dysfunction risk factors before and after CoA repair were used in the analysis. They confirmed that turbulence fluctuations, the direct jet impact and/or the combination of both could lead to initiation of post-stenosis dilatation which may instigate

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Numerical analysis of coronary artery bypass grafts: An over view

Cited by 76 publications

References 72 publications

Fluid dynamics in helical geometries with applications for by-pass grafts

Fluid dynamics in helical geometries with applications for by-pass grafts

Analysis of Computational Fluid Dynamics and Particle Image Velocimetry Models of Distal-End Side-to-Side and End-to-Side Anastomoses for Coronary Artery Bypass Grafting in a Pulsatile Flow

Cardiovascular haemodynamics: Advancement of numerical and experimental diagnostic tools

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