At present, there are no experimental methods that allow for the complete direction-dependent mechanical characterization of tubes. This considerably limits the parameterization of complex, anisotropic material models. The present study introduces a new approach to overcome these limitations: tube sections are first flattened into a planar geometry; then, samples for uniaxial testing are taken out of the flattened tube section and used for parameter identification. In this paper, special emphasis is placed on the intermediate step of flattening, which is investigated in detail both numerically and experimentally. Flattening by pressing is identified as the most advantageous of several options, and the procedure is optimized by numerical simulations that address springback compensation. Experimental validation is performed on tubes (steel E235) with a diameter of 60 mm and an average wall thickness of 1.524 mm. Tube sections are successfully flattened in a custom-built tool with only small remaining out-of-plane displacements after flattening. The numerically predicted pressing force curves agree very well with the experimental data.