In recent years, the advancement of science and technology, particularly the development of flight control technology, has driven the progress of aircraft technology, which facilitates the rapid development of many kinds of aircraft. Pneumatics, the mechanics of gas flow, is used to study aerodynamics. In the design and manufacturing of aircraft, gas flow has a significant impact on the movement, control, attitude, stability, and other aspects of the aircraft. This paper describes the basic Pneumatics principles in aircraft design: aerodynamics is the discipline that studies the interaction between airflow and aircraft, it is the core foundation of aircraft external shape design, a pivotal discipline in overall design, and a prerequisite for conducting design analyses in fields, it plays a crucial role in aircraft design and force analysis for the aircraft, and this paper also introduces the aerodynamic layout design and aerodynamic characteristics of tilt-rotor Unmanned Aerial Vehicle (UAV), multi-rotor aircraft and bionic flapping wing aircraft, so as to offer some references for future study of air vehicles.