Numerical design studies on a novel electrostimulative osteosynthesis system for the mandible

Abstract

Fractures or other major bone defects in the mandible are commonly treated by mounting a reconstruction plate at the fracture site. To avoid complications due to loosening of the implant or the fixation screws, electrical stimulation presents a possibility to accelerate bone healing. The aim of this study was to investigate different combinations of activated electrodes and plate designs regarding their feasibility for electrostimulation of the mandibular bone. The electric field distribution for multiple implant designs was computed using the finite element method. The results suggest that the electrode insulation renders a crucial parameter, which influences substantially the stimulation impact and its power consumption.

Establishment of a Numerical Model to Design an Electro-Stimulating System for a Porcine Mandibular Critical Size Defect

“…Although we already proposed preliminary numerical models of an electrically stimulated human mandible [45,46], the current work for the first time examines an electrical stimulation system for the regeneration of critical size defects in mandibular bone suitable for practical application in validation experiments. Specifically, in the current study we focus on a numerical model of a porcine, i.e., minipig mandible.…”

Addressing Model Uncertainties in Finite Element Simulation of Electrically Stimulated Implants for Critical-Size Mandibular Defects

“…The presented research is part of the collaborative research center SFB 1270/2 ELAINE on electrically active implants (https://www.elaine.uni-rostock.de/en/), which focuses on improving patient-specific therapies through novel electrostimulating implants for bone, cartilage, and deep brain stimulation. In previous research, we have investigated fundamental aspects of mandibular electrical stimulation in preliminary human in silico models [18], [19]. However, before entering clinical use, new therapeutic devices typically undergo in vitro and then in vivo testing to assess their functionality and safety.…”