Exploration related to chemical processes in nanomaterial flows contains astonishing features. Nanoparticles have unique physical and chemical properties, so they are continuously used in almost every field of nanotechnology and nanoscience. The motive behind this article is to investigate the Cross nanofluid model along with its chemical processes via auto catalysts, inclined magnetic field phenomena, heat generation, Brownian movement, and thermophoresis phenomena over a symmetric shrinking (stretching) wedge. The transport of heat via nonuniform heat sources/sinks, the impact of thermophoretic diffusion, and Brownian motion are considered. The Buongiorno nanofluid model is used to investigate the impact of nanofluids on fluid flow. Modeled PDEs are transformed into ODEs by utilizing similarity variables and handling dimensionless ODEs numerically with the adoption of MATLAB’s developed bvp4c technique. This software performs a finite difference method that uses the collocation method with a three-stage LobattoIIIA strategy. Obtained outcomes are strictly for the case of a symmetric wedge. The velocity field lessens due to amplification in the magneto field variable. Fluid temperature is amplified through the enhancement of Brownian diffusion and the concentration field improves under magnification in a homogeneous reaction effect.