Numerical Investigation of Centrifugal Blood Pump Cavitation Characteristics with Variable Speed

Teng, Jing; Cheng, Yujiao; Wang, Fangqun; Wang, Bao; Zhou, Lian

doi:10.3390/pr8030293

Cited by 13 publications

(11 citation statements)

References 25 publications

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“…Also, they concluded installing splitter blades on the blood pump leads to raises in the head pressure. Jing et al 2020) analyzed the effects of the variable speed on the steady cavitating flow and stated that an increase of the impeller speed generates the vortex cavitation which affects the sheet cavitation on the impeller. It also increases the blockage effect near the hub and impeller.…”

Section: Centrifugal Blood Pumpmentioning

confidence: 99%

Experimental and numerical investigation of different geometrical parameters in a centrifugal blood pump

Hosseini

Keshmiri

2022

Res. Biomed. Eng.

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Purpose Due to the importance of public health and economics, cardiovascular disease has become one of the most important debates and challenges for scientists. However, few studies have been done to address this challenge. The main objective of this document is to provide an optimal model to improve the performance of the left ventricular assist device and reduce costs. In this way, in the present study, the experimental and numerical procedures were developed to analyze the effects of the geometrical features and operational parameters on the performance of a centrifugal blood pump (CBP). Methods In order to achieve this aim, first, experimental tests were carried out to study the influence of the working fluid temperature and the rotational speed on the CBP. Subsequently, the performance of the CBP was assessed using computational fluid dynamics (CFD), and comparison was made against the experimental data. In addition, the influence of mounting an inducer on the overall performance of CBP was also investigated. Results Good agreement between the CFD and the data was obtained. The CFD results showed that increasing the fluid temperature and rotational speed leads to an increase in the hydraulic efficiency, pressure difference, and power. In addition, the reduction of the pressure difference and hydraulic efficiency with increasing the surface roughness was observed. While mounting an inducer on the pump did not significantly impact its overall performance, the highest value of the wall shear stress dropped moderately on the impeller and, therefore, unveiled the possibility of improving the performance of such designs.

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Section: Centrifugal Blood Pumpmentioning

confidence: 99%

Experimental and numerical investigation of different geometrical parameters in a centrifugal blood pump

Hosseini

Keshmiri

2022

Res. Biomed. Eng.

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“…According to the characteristic curve of the centrifugal blood pump and the relationship among the head, flow, and speed, the mathematical model expression of the centrifugal blood pump was obtained [ 37 ].

where H is the head of the pump;

are the pump’s out pressure and inlet pressure, respectively; Q is the pump flow;

is the rate of change of pump flow; ω is the pump speed;

is the pump resistance coefficient with a value of −0.391;

is the pump inertia coefficient with a value of −0.00183; and

is the correlation constant of the pump, with a value of 1.147 ×

.…”

Section: Methodsmentioning

confidence: 99%

Control Strategy Design of a Microblood Pump Based on Heart-Rate Feedback

et al. 2022

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Based on the nonlinear relationship between heart rate and stroke volume, a flow model of left ventricular circulation was improved, and a variable-speed blood-pump control strategy based on heart-rate feedback was proposed. The control strategy was implemented on a system combining the rotary blood pump and blood circulation models of heart failure. The aortic flow of a healthy heart at different heart rates was the desired control goal. Changes in heart rate were monitored and pump speed was adjusted so that the output flow and aortic pressure of the system would match a normal heart in real time to achieve the best auxiliary state. After simulation with MATLAB, the cardiac output satisfied the ideal perfusion requirements at different heart rates, and aortic pressure demonstrated lifting and had good pulsatile performance when a variable-speed blood pump was used. The coupled model reflected the relationship between hemodynamic parameters at different heart rates with the use of the variable-speed blood pump, providing a theoretical basis for the blood-pump-assisted treatment of heart failure and the design of physiological control strategies.

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“…exposure time of the impulse vibration [45]. Fig 5D illustrates the duration of deflection higher than 1.5 mm.…”

Section: Plos Onementioning

confidence: 98%

A low-cost, open-source centrifuge adaptor for separating large volume clinical blood samples

et al. 2022

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Blood plasma separation is a prerequisite in numerous biomedical assays involving low abundance plasma-borne biomarkers and thus is the fundamental step before many bioanalytical steps. High-capacity refrigerated centrifuges, which have the advantage of handling large volumes of blood samples, are widely utilized, but they are bulky, non-transportable, and prohibitively expensive for low-resource settings, with prices starting at $1,500. On the other hand, there are low-cost commercial and open-source micro-centrifuges available, but they are incapable of handling typical clinical amounts of blood samples (2-10mL). There is currently no low-cost CE marked centrifuge that can process large volumes of clinical blood samples on the market. As a solution, we customised the rotor of a commercially available low-cost micro-centrifuge (~$125) using 3D printing to enable centrifugation of large clinical blood samples in resource poor-settings. Our custom adaptor ($15) can hold two 9 mL S-Monovette tubes and achieve the same separation performance (yield, cell count, hemolysis, albumin levels) as the control benchtop refrigerated centrifuge, and even outperformed the control in platelet separation by at least four times. This low-cost open-source centrifugation system capable of processing clinical blood tubes could be valuable to low-resource settings where centrifugation is required immediately after blood withdrawal for further testing.

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Numerical Investigation of Centrifugal Blood Pump Cavitation Characteristics with Variable Speed

Cited by 13 publications

References 25 publications

Experimental and numerical investigation of different geometrical parameters in a centrifugal blood pump

Experimental and numerical investigation of different geometrical parameters in a centrifugal blood pump

Control Strategy Design of a Microblood Pump Based on Heart-Rate Feedback

A low-cost, open-source centrifuge adaptor for separating large volume clinical blood samples

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