A CFD-based assessment of the low speed high lift performance of an over-the-wing mounted engine installations for a short range airliner with STOL capabilities is presented in this paper. The configuration is representative for a 100 passenger aircraft and characterized by pylon mounted over-the-wing installed UHBR-engines. The high lift system features active segmented and highly deflected Coanda flaps and a specifically designed droop nose at the leading edge of the wing. The study is part of the Collaborative Research Center 880 that develops technologies and configurations with quite STOL capabilities. The layout of the high lift system is described, together with the numerical approach and results for the considered test case. The objective of the present study is to investigate a short chord active plain flap in landing configuration and assess the maximum lift capabilities against target values from preliminary design studies of the CRC 880. It is a first step towards a more comprehensive assessment of variants of the high lift system. With the typical lift generation for a circulation control supported high lift system, the analysis of the stall behavior reveals a favorable smooth lift breakdown starting at the inner wing. Yet, the maximum lift properties fall short of the target value, so that an enlarged chord flap will be considered as a next step to comply with the maximum lift requirements.