The paper presents an investigation of the influence of chemical reaction on steady mixed convection MHD flow of Non-Newtonian micropolar nanofluid past a permeable vertical plate. The effect of Thermophoresis parameter and Brownian motion parameter are incorporated in the energy equation and concentration equation. The governing partial differential equations are converted into a system of ordinary differential equations using similarity transformations. The sysyem of linear equations are solved by using the implicit finite difference method. The effect of different parameters on the dimensionless velocity, temperature and concentration are shown graphically and analyzed. The effect of physical parameters such as material parameter K, suction parameter A, Prandtl number Pr, radiation parameter R, thermophoresis parameter Nt, Brownian motion parameter Nb, chemical reaction parameter and magnetic parameter Ha are also being numerically investigated and analyzed.