Numerical investigation on layout optimization of obstacles in a three-dimensional passive micromixer

Chen, Xueye; Zhao, Zhongyi

doi:10.1016/j.aca.2017.01.066

Cited by 126 publications

(39 citation statements)

References 15 publications

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“…This subject is repeated for the cases without expansion parts at (

) with a difference. Even though the inertial term is 10 times stronger than the viscous term, it is not enough to cause secondary flows and Dean vortices, which are considered as the main mixing factors in a laminar regime that usually takes place at (

) [ 23 ].…”

Section: Resultsmentioning

confidence: 99%

“…The proposed mixer, shown in Figure 1 , minimizes the space consumption and does not increase the pressure drop as much as some types of micromixers such as split and recombine mixers and mixers with obstacles on the path of the fluid [ 17 , 18 , 22 , 23 ].…”

Section: Mixer Design and Numerical Analysismentioning

confidence: 99%

“…Li et al [ 22 ] studied the impact of putting obstacles on the path of the flow and showed that the placement, size and the angle of the obstacles can determine the performance of mixers in the range of 1 ≤ Re ≤ 10, but in higher flow rates the configuration of the obstacles does not play such an important role. Chen et al [ 23 ] included a pattern of pillars in the flow path of the micromixer. The study clarified the relation between the Peclet number and the mixing efficiency.…”

Section: Introductionmentioning

confidence: 99%

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Novel Variable Radius Spiral–Shaped Micromixer: From Numerical Analysis to Experimental Validation

et al. 2018

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A novel type of spiral micromixer with expansion and contraction parts is presented in order to enhance the mixing quality in the low Reynolds number regimes for point-of-care tests (POCT). Three classes of micromixers with different numbers of loops and modified geometries were studied. Numerical simulation was performed to study the flow behavior and mixing performance solving the steady-state Navier–Stokes and the convection-diffusion equations in the Reynolds range of 0.1–10.0. Comparisons between the mixers with and without expansion parts were made to illustrate the effect of disturbing the streamlines on the mixing performance. Image analysis of the mixing results from fabricated micromixers was used to verify the results of the simulations. Since the proposed mixer provides up to 92% of homogeneity at Re 1.0, generating 442 Pa of pressure drop, this mixer makes a suitable candidate for research in the POCT field.

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“…This subject is repeated for the cases without expansion parts at (

) [ 23 ].…”

Section: Resultsmentioning

confidence: 99%

Section: Mixer Design and Numerical Analysismentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Novel Variable Radius Spiral–Shaped Micromixer: From Numerical Analysis to Experimental Validation

et al. 2018

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“…Generally, these methods can be divided into two categories: active methods and passive methods [4]. Passive methods usually utilize various geometries [5–17] of microchannels and different shapes of obstacles [18–23] or grooves [24–27] placed in microchannels to disturb the laminar flow for vortex formation. Passive methods do not need external energy sources, but the channels of such methods usually need to be designed with complex structures, thereby increasing the fabrication difficulty.…”

Section: Introductionmentioning

confidence: 99%

Electrokinetic‐vortex formation near a two‐part cylinder with same‐sign zeta potentials in a straight microchannel

2020

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Vortex formation near a two-part cylinder with zeta potentials of different values but the same sign under an external DC electric field is numerically investigated in this paper. The cylinder, inserted in a straight microchannel filled with an aqueous solution, is composed of an upstream part and a downstream part. When a DC electric field is applied in the channel, under certain conditions, the vortex will form near the cylinder due to the different velocities of electroosmotic flow generated on the cylinder surface. The numerical results reveal that the larger the velocity difference of electroosmotic flow generated on the two-part cylinder and the smaller the channel width, the more conducive to vortex formation in the channel. In addition, if the zeta potential ratios of cylinder downstream part to upstream part and channel wall to cylinder upstream part are unchanged, the DC electric field strength and the zeta potential value do not affect the pattern of vortices formed in the channel. This study provides a way for vortex formation in microchannels and has the potential application in microfluidic devices.

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“…When Re increases to an extent ( Re > 300) [ 18 , 19 , 20 ], rapid mixing can be achieved for a T-mixer because the fluids coming from the inlets can generate an asymmetric flow at the entrance of the mixing channel. Therefore, in order to obtain efficient mixing at an extensive range of Reynolds numbers, many researchers have studied various approaches to micromixer design, including bent or curved channel arrangement [ 21 , 22 , 23 , 24 ], wall structures [ 25 , 26 , 27 ], obstacles within the channel [ 28 , 29 ], and modified T-shaped channels [ 30 , 31 ].…”

Section: Introductionmentioning

confidence: 99%

Mixing Performance of a 3D Micro T-Mixer with Swirl-Inducing Inlets and Rectangular Constriction

Zhang

Luo

2018

Micromachines

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In this paper, three novel 3D micro T-mixers, namely, a micro T-mixer with swirl-inducing inlets (TMSI), a micro T-mixer with a rectangular constriction (TMRC), and a micro T-mixer with swirl-inducing inlets and a rectangular constriction (TMSC), were proposed on the basis of the original 3D micro T-mixer (OTM). The flow and mixing performance of these micromixers was numerically analyzed using COMSOL Multiphysics package at a range of Reynolds numbers from 10 to 70. Results show that the three proposed 3D micro T-mixers have achieved better mixing performance than OTM. Due to the coupling effect of two swirl-inducing inlets and a rectangular constriction, the maximum mixing index and pressure drop appeared in TMSC among the four micromixers especially; the mixing index of TMSC reaches 91.8% at Re = 70, indicating that TMSC can achieve effective mixing in a short channel length, but has a slightly higher pressure drop than TMSI and TMRC.

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Numerical investigation on layout optimization of obstacles in a three-dimensional passive micromixer

Cited by 126 publications

References 15 publications

Novel Variable Radius Spiral–Shaped Micromixer: From Numerical Analysis to Experimental Validation

Novel Variable Radius Spiral–Shaped Micromixer: From Numerical Analysis to Experimental Validation

Electrokinetic‐vortex formation near a two‐part cylinder with same‐sign zeta potentials in a straight microchannel

Mixing Performance of a 3D Micro T-Mixer with Swirl-Inducing Inlets and Rectangular Constriction

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