2016
DOI: 10.1016/j.jmbbm.2016.02.011
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Numerical modeling of experimental human fibrous cap delamination

Abstract: Fibrous cap delamination is a critical process during the rupture of atherosclerotic plaque, which often leads to severe life-threatening clinical consequences such as myocardial infarction or stroke. In this study a finite element modeling and simulation approach is presented that enables the study of fibrous cap delamination experiments for the purpose of understanding the fibrous cap delamination process. A cohesive zone model (CZM) approach is applied to simulate delamination of the fibrous cap from the un… Show more

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Cited by 11 publications
(18 citation statements)
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“…This study focuses on the comparison of four different shapes (triangular, trapezoidal, linear-exponential, and exponential-linear) of CZM in modeling the arterial medial layer peeling. Meanwhile, as a continuation of the previous studies, four types of CZM laws are used to model the delamination fracture of atherosclerotic plaque and fibrous cap [14,15]. The findings of this study will help to study the influence of cohesive law shapes on the tearing propagation behavior in the medial layer of the arterial tissue.…”
Section: Introductionmentioning
confidence: 80%
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“…This study focuses on the comparison of four different shapes (triangular, trapezoidal, linear-exponential, and exponential-linear) of CZM in modeling the arterial medial layer peeling. Meanwhile, as a continuation of the previous studies, four types of CZM laws are used to model the delamination fracture of atherosclerotic plaque and fibrous cap [14,15]. The findings of this study will help to study the influence of cohesive law shapes on the tearing propagation behavior in the medial layer of the arterial tissue.…”
Section: Introductionmentioning
confidence: 80%
“…The aim of this study is to compare the four different shapes (triangular, trapezoidal, linear-exponential, and exponential-linear) of the CZM in modeling the arterial medial layer peeling (Figures 3 and 4). Moreover, four types of CZM laws were used to model the delamination of atherosclerotic plaque [14] ( Figure 5) and fibrous cap [15] ( Figure 6).…”
Section: Results Comparison and Discussionmentioning
confidence: 99%
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