The characteristics of series-flow between two consecutive tunnels with distance ranging from 20 m to 250 m are explored by computational fluid dynamics (CFD) parametric simulations of structure and operation parameters. The research indicates that series-flow can be considered the three-dimensional wall jet diffusion of upstream tunnel pollutants under the effects of the negative pressure area of the downstream tunnel entrance. The jet characteristics are primarily related to the tunnel distance between upstream and downstream tunnels and hydraulic diameters, and only influenced by the negative pressure in the area very close to downstream entrance where the tunnel air velocity ratio, i.e., the velocity of upstream tunnel air divided by the velocity of downstream tunnel air, decides the degree of the influence. If ignoring the effects of ambient wind and traffic flow, the series-flow ratio decreases with the increasing of parameters of the normalized tunnel distance, i.e., the tunnel distance divided by tunnel hydraulic diameter, and the tunnel air velocity ratio. Based on the three-dimensional wall jet theory, a series-flow model covering all jet characteristic sections is built. The experiment results indicate that the model applies to consecutive tunnels with any spacing and exhibits higher prediction accuracy.