Numerical Simulation of The Impact of Chorda Tendinea Rapture on the Mitral Valve Leaflets Stress by Finite Element Method

Abedini, Hasan; Moghadam, Adel Johari

doi:10.13005/bpj/930

Cited by 1 publication

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“…Abedini and Johari Moghadam used Mooney-Rivlin hyperelastic model as material properties of leaflets’ tissue for the first time among all models. 12 FE methods are suitable for the simulation of quasi-static events such as opened or closed valves. However, to accurately simulate transient dynamics and evaluate hemodynamics parameters, FSI models are required.…”

Section: Introductionmentioning

confidence: 99%

Comparative modeling of the mitral valve in normal and prolapse conditions

Razavi

Talebi

2023

Bioimpacts

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Introduction: Computational modeling is one of the best non-invasive approaches to predicting the functional behavior of the mitral valve (MV) in health and disease. Mitral valve prolapse (MVP) due to partial or complete chordae tendineae rapture is the most common valvular disease and results in mitral regurgitation (MR). Methods: In this study, Image-based fluid-structure interaction (FSI) models of the human MV are developed in the normal physiological and posterior leaflet prolapse conditions. Detailed geometry of the healthy human MV is derived from Computed Tomography imaging data. To provide prolapse condition, some chords attached to the posterior leaflet are removed from the healthy valve. Both normal and prolapsed valves are embedded separately in a straight tubular blood volume and simulated under physiological systolic pressure loads. The Arbitrary Lagrangian-Eulerian finite element method is used to accommodate the deforming intersection boundaries of the blood and MV. Results: The stress values in the mitral components, and also flow patterns including the regurgitant flow rates are obtained and compared in both conditions through the simulation. These simulations have the potential to improve the treatment of patients with MVP, and also help surgeons to have more realistic insight into the dynamics of the MV in health and prolapse. Conclusion: In the prolapse model, computational results show incomplete leaflet coaptation, higher MR severity, and also a significant increment of posterior leaflet stress compared to the normal valve. Moreover, it is found more deviation of the regurgitant jet towards the left atrium wall due to the posterior leaflet prolapse.

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Section: Introductionmentioning

confidence: 99%