The computational simulation of unsteady Fluid-Structure Interaction (FSI) problems continues to pose many challenges to the computational community. Of the many fundamental elements to partitioned FSI approaches, the most challenging aspects include the treatment of moving components within a fluid dynamics simulation, the consistent and stable transfer of loads between solvers, and the lack of automation in the process. The majority of this paper addresses the first of these problems by presenting simulations of prescribed relative motion through stationary, unstructured Cartesian meshes. Numerical accuracy is investigated through comparisons of moving body simulations to stationary simulations. It is shown that the numerical error increases with moving body simulations, as a result of an increase in wave speed with respect to the mesh. The second FSI component is investigated by considering the partitioned coupling of a 1-D elastic piston, as well as the vortex-induced vibrations of an elastic cylinder in laminar flow. The coupling scheme is analyzed by considering numerical accuracy, stability, and numerical dissipation. The simulations demonstrate accurate predictions in both the response frequencies and the trajectories.