<abstract><p>In this article, a collocation technique based on quintic trigonometric B-spline (QTB-spline) functions was presented for homogeneous as well as the nonhomogeneous extended Fisher-Kolmogorov (F-K) equation. This technique was used for space integration, while the time-derivative was discretized by the usual finite difference method (FDM). To handle the nonlinear term, the process of Rubin-Graves (R-G) type linearization was employed. Three examples of the homogeneous extended F-K equation and one example of the nonhomogeneous extended F-K equation were considered for the analysis. Stability analysis and numerical convergence were also discussed. It was found that the discretized system of the extended F-K equation was unconditionally stable, and the projected technique was second order accurate in space. The consequences were portrayed graphically to verify the accuracy of the outcomes and performance of the projected technique, and a relative investigation was accomplished graphically. The figured results were found to be extremely similar to the existing results.</p></abstract>