A theory-based prediction method was used to estimate the friction factor and heat transfer rate in the turbulent flow of a helically coiled tube. The secondary flow produced by a centrifugal force improves heat and mass transfer; therefore, spiral coil pipes are widely used in a variety of industrial applications. The law of the wall and the Reynolds analogy, which states that momentum transfer in a turbulent flow is equivalent to heat transfer, were used in this theoretical method. The logarithmic law was used to characterize the velocity profile in the turbulence-dominated region, and the local wall shear stress variation throughout the circumference of the helical tube wall was considered. The friction factor and heat transfer in the turbulent flow of the helically coiled tube were accurately predicted by the model. Using the Reynolds analogy, the local Nusselt number in the circumferential direction of the helical tube wall was determined. The effect of decreasing local heat transfer within the tube while increasing heat transfer outside the tube was quantified. The analogy between the momentum flux and the heat flux in the turbulent flow of the straight tube was also proven to be applicable to the spiral tube.