The aim of this paper is to provide the softwarebased materials selection approach for the micro channel heat exchanger for high-temperature industrial waste heat recovery. Industrial heat processing and heat recovery places increasing demand for material performance in extreme conditions. These extreme conditions accelerate the material's degradation in turn leading to performance and efficiency reduction. Therefore the development of new compatible materials demand material qualification for the miniaturized technology to function over a long period of time with full efficiency. This paper proposes methodology for the material identification and selecting appropriate material for the micro channel heat exchanger to recover high-temperature (>500 ℃) industrial waste heat. Thermally stable materials such as aluminum nitride, silicon carbide, alumina, tungsten carbide, tungsten alloys, and nickel and TZM alloys were observed to perform exceptionally well in extreme condition. Thus silicon carbide, aluminum nitride and molybdenum TZM alloys were selected as the most promising materials for micro channel heat exchanger recover hightemperature (500-750 ℃) waste heat from different industries.