In the present study, galvanized High Strength Interstitial Free (HIF) steel sheets, and Dual Phase (DP780) steel sheets were used for the investigations. Resistance spot weld joints were fabricated between dissimilar steel sheets. The variation in dynamic resistance (DR) with the change in welding process parameters such as weld current, weld time and electrode force were used for establishing the range of adequate weld nugget formation parameters. Effect of these parameters over tensile strength, nugget diameter and the observed failure mode was studied using one factor at a time (OFAT) approach. Microstructure and hardness of parent metal, fusion & HAZ region has also been studied.