The influence of the improvement of the finned tube radiator unit structure on the fluid flow and heat transfer effect of the locomotive was studied. A saw-toothed fin structure with aluminum instead of copper was proposed to keep the position and size of the flat copper hot water pipe unchanged. CFD simulation analysis was carried out by ICEPAK17.0, under the conditions of an ambient temperature of 24.6 °C, atmospheric pressure of 85,040 Pa and air density ρ = 0.94 kg/m3, to compare the changes of velocity field, temperature field, turbulence field and field synergy angle. The sawtooth structure of the new heat sink increases the turbulence effect of the fluid, reduces the thickness of the outer boundary layer of the water pipe, and strengthens the heat transfer effect of the radiator. Finally, the baffle height, wing window width and sawtooth angle of the sawtooth structure were selected, and the heat transfer coefficient and pressure under three conditions of low, medium and high were used as indexes to analyze the influence of each parameter on the performance of the radiator. The results show that the heat dissipation effect of the serrated aluminum sheet is higher than that of the copper sheet, the heat transfer coefficient is increased by about 1.3%, the average pressure is reduced, the turbulence performance is improved, the synergy angle is reduced by about 2.3°, and the new radiator has better performance. The fin factor has the greatest influence on the heat transfer coefficient and the least influence on the pressure. When the baffle is about 0.15 mm high, the heat transfer coefficient is the largest, and the height change has the highest effect on the pressure. The included Angle factor has the least influence on the heat transfer effect, and the influence on the pressure is higher. By changing the fin window structure, the thermal performance of the finned tube radiator can be improved.