The role of the perioperative nurse manager was complex and the content and focus of the role was unclear. Perioperative nurse managers are responsible for leading and managing the operating room at an operational and tactical level. As research in this area is limited, further discussion is needed to describe the role of the perioperative nurse manager. This viewpoint aims to identify the role of the perioperative nurse manager in the operating room. To answer the role of the perioperative nurse manager, there are several skills and tasks in the operating room. These required skills are coordination skills, collaboration skills, communication skills, decision making skills, leadership skills, management skills, nursing skills, and recruitment skills. These required tasks are aligned with the organizational goal, client-centered care management, daily unit operations management, perioperative care development, financial management, human resource management, and standard of care. Research lacks a clear description of the role of the perioperative nurse manager in the perioperative settings. However, the role of the nurse manager develops through knowledge, skills, and experience in the perioperative setting. Through these aspects, it is possible to develop competence in the skills and tasks undertaken while working in the perioperative setting.