Nutraceutical Vegetable Oil Nanoformulations for Prevention and Management of Diseases

Vergallo, Cristian

doi:10.3390/nano10061232

Cited by 33 publications

(18 citation statements)

References 129 publications

(173 reference statements)

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“…Plant-derived oils contain the two precursors of the ω6 and ω3 families, i.e., linoleic and alpha-linolenic acids (LA, ALA), together with protective micronutrients, such as tocopherols, carotenoids, phytosterol, beta-carotene, nitrogen compounds, minerals (e.g., phosphorous, magnesium, manganese, copper, iron, zinc, and potassium), vitamins, and phenolic compounds (Vergallo, 2020). Marine-derived oils, in particular oils from fatty fish, are an important source of ω3 fatty acids, predominantly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA; Abedi and Sahari, 2014).…”

Section: Introductionmentioning

confidence: 99%

Bioactive Compounds in Edible Oils and Their Role in Oxidative Stress and Inflammation

et al. 2021

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Diet and inflammatory response are recognized as strictly related, and interest in exploring the potential of edible fats and oils for health and chronic diseases is emerging worldwide. Polyunsaturated fatty acids (PUFAs) present in fish oil (FO), such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), may be partly converted into oxygenated bioactive lipids with anti-inflammatory and/or pro-resolving activities. Moreover, the co-presence of phenolic compounds and vitamins in edible oils may prevent the development of chronic diseases by their anti-inflammatory, antioxidant, neuroprotective, and immunomodulatory activities. Finally, a high content in mono-unsaturated fatty acids may improve the serum lipid profile and decrease the alterations caused by the oxidized low-density lipoproteins and free radicals. The present review aims to highlight the role of lipids and other bioactive compounds contained in edible oils on oxidative stress and inflammation, focusing on critical and controversial issues that recently emerged, and pointing to the opposing role often played by edible oils components and their oxidized metabolites.

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Section: Introductionmentioning

confidence: 99%

Bioactive Compounds in Edible Oils and Their Role in Oxidative Stress and Inflammation

et al. 2021

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“…It is the growth of aging populations, environmental pollution, and life pressures that leads to disease and economic burdens. With [78,79]. the development of science and technology, antioxidant bioactive substances are exploited more effectively and thoroughly.…”

Section: Opportunity and Challengementioning

confidence: 99%

Functional-Antioxidant Food

Xuan¹,

Ánh²,

Quan³

et al. 2021

Functional Foods - Phytochemicals and Health Promoting Potential

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Nowadays, people face many different dangers, such as stress, unsafety food, and environmental pollution, but not everyone suffers. Meanwhile, free radicals are the biggest threat for humans because they lead to over 80 different diseases composed of aging. Free radicals can only be eliminated or minimized with antioxidant foods or antioxidants. The chapter on the functional-antioxidant food presents the antioxidant functional food concept, the classification, the structure, and the extraction process of antioxidant ingredients. Various antioxidant substances such as protein (collagen), polysaccharides (fucoidans, alginates, glucosamines, inulins, laminarins, ulvans, and pectins), and secondary metabolites (polyphenols (phlorotannins, lignins, polyphenols), alkaloids, and flavonoids) also present. The production technology, the mechanism, the opportunity, and the challenge of antioxidants functional food also present in the current chapter. The current chapter also gives the production process of functional-antioxidant food composed of the capsule, the tablet, tube, the pills, the powder, and the effervescent tablet.

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“…Different technological approaches have been developed to synthesize stable nanosystems and, among them, methods using vegetable oils have stood out. Vegetable oils have been used to design multifunctional nanostructured carriers with multiple health benefits [ 20 , 21 , 22 , 23 ]. These oils possess several advantages over synthetic compounds because of their constituents, such as triglycerides, fatty acids, phenolics, and carotenoids.…”

Section: Introductionmentioning

confidence: 99%

Eco-Friendly Production of AuNPs and Their Impact on the Oil Oxidative Stability

et al. 2021

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Vegetable oils have been used for different applications and, more recently, as an active host medium to obtain nanoparticles for employment in bionanotechnological applications. Nevertheless, oils are very susceptible to oxidation during production, storage, and transportation because of their chemical composition. Consequently, any modification in their production must be accompanied by an analysis of the oxidative stability. In this study, naked and biocompatible gold nanoparticles (AuNPs) were grown on sunflower oil during sputtering deposition using different deposition times. Size and morphology were determined by transmission electron microscopy (TEM) and their concentrations were found by inductively coupled plasma-optical emission spectroscopy (ICP-OES). Rancimat® method was employed to evaluate the AuNPs influence on the oxidative stability of the vegetable oil. Well-dispersed quasi-spherical NPs were produced with a mean diameter in the 2.9–3.7 nm range and they were concentration-dependent on the deposition time. A concentration of about 11 mg/L, 38 mg/L, and 225 mg/L of AuNPs was obtained for a deposition time of 5 min, 15 min, and 30 min, respectively. The results also revealed that AuNPs negatively affected the oxidative stability of the sunflower oil and exponentially reduced the induction period (IP) with the increase in AuNPs content. IP reductions of 63%, 77%, and 81% were determined for the AuNPs containing samples at 11 mg/L, 38 mg/L, and 225 mg/L. For the first time, it is reported that naked AuNPs promote the rapid degradation of vegetable oil and this points out the need for attention relative to the quality of vegetable oils used to host metal nanoparticles.

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Nutraceutical Vegetable Oil Nanoformulations for Prevention and Management of Diseases

Cited by 33 publications

References 129 publications

Bioactive Compounds in Edible Oils and Their Role in Oxidative Stress and Inflammation

Bioactive Compounds in Edible Oils and Their Role in Oxidative Stress and Inflammation

Functional-Antioxidant Food

Eco-Friendly Production of AuNPs and Their Impact on the Oil Oxidative Stability

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