Nutraceuticals

Ballou, Michael; Davis, Emily M.; Kasl, B A

doi:10.1016/j.cvfa.2019.08.004

Cited by 32 publications

(11 citation statements)

References 97 publications

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“…Morbidity and mortality resulting from BRD continue to be the most economically significant problems facing the feedlot industry ( Duff and Galyean, 2007 ; Wilson et al., 2017 ; Peel, 2020 ). Incorporating nutraceuticals into diets of feedlot cattle, especially during the receiving period, may be advantageous, particularly as a management tool to aid in improving animal performance and decreasing morbidity ( Duff and Galyean, 2007 ; Ballou et al., 2019 ;). Research also suggests the supplementation of nutraceuticals in diets of newly received cattle may have the potential to decrease the dietary adaption period, allowing cattle to consume a more energy-dense diet earlier in the finishing period ( Swanson et al., 2018 ).…”

Section: Introductionmentioning

confidence: 99%

Effects of feeding CLOSTAT (Bacillus subtilis PB6) on the clinical health, performance, and carcass characteristics of feedlot steers1

Ryan

DeSocio

Youngers

et al. 2023

Translational Animal Science

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The objectives of this experiment were to evaluate the effects of feeding Bacillus subtilis PB6 on clinical health, performance, and carcass characteristics of feedlot steers. Bos indicus crossbred steer calves [n = 397; 342 kg initial body weight (BW)] were randomly assigned to pens by initial BW; pens (n = 24) were randomly assigned to 1 of 2 of the following experimental treatments: 1) no supplemental dietary direct-fed microbial, control (CON; n = 12 pens); or 2) 13 g/steer daily B. subtilis PB6 (CLO; CLOSTAT ®, Kemin Industries, Des Moines, IA; n = 12 pens). Steers were housed in 12.2 × 30.5 m soil surfaced pens; pen served as the experimental unit. The percentage of cattle treated once or twice for bovine respiratory disease (BRD) did not differ among treatments (P ≥ 0.27); BRD mortality also did not differ between CON and CLO (P = 0.34). During the receiving period, final BW (P = 0.97), average daily gain (ADG; P = 0.91), dry matter intake (DMI; P = 0.77), and gain:feed (P = 0.79) were not different among treatments. There was a tendency (P = 0.09) for CLO supplemented steers to be 14% more efficient from d 0 to 14 of the receiving period. Final BW, overall finishing phase ADG, and DMI did not differ by treatment (P ≥ 0.14); ADG was 0.14 kg greater for CLO than CON (P = 0.03) from d 29 to 56 of the finishing period. Gain: feed tended (P = 0.07) to be 7% greater (0.144 vs 0.141) for CLO than CON throughout the duration of the finishing period, and 6.7% greater (P = 0.08; 0.152 for CLO vs. 0.150 for CON) for the entirety of the experiment. Carcass traits did not differ among treatments (P ≥ 0.31). The results of this experiment suggest that supplementing 13 g/steer daily B. subtilis PB6 may improve feed efficiency in feedlot cattle.

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Section: Introductionmentioning

confidence: 99%

Effects of feeding CLOSTAT (Bacillus subtilis PB6) on the clinical health, performance, and carcass characteristics of feedlot steers1

Ryan

DeSocio

Youngers

et al. 2023

Translational Animal Science

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“…Additionally, several multidrug resistance bacteria have emerged making, this crisis global [32][33][34]. Nutraceuticals will be required to reduce the use of antibiotics [35].…”

Section: Intestinal Microbiota In Poultrymentioning

confidence: 99%

Probiotics, Prebiotics, and Phytogenic Substances for Optimizing Gut Health in Poultry

et al. 2022

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The gut microbiota has been designated as a hidden metabolic ‘organ’ because of its enormous impact on host metabolism, physiology, nutrition, and immune function. The connection between the intestinal microbiota and their respective host animals is dynamic and, in general, mutually beneficial. This complicated interaction is seen as a determinant of health and disease; thus, intestinal dysbiosis is linked with several metabolic diseases. Therefore, tractable strategies targeting the regulation of intestinal microbiota can control several diseases that are closely related to inflammatory and metabolic disorders. As a result, animal health and performance are improved. One of these strategies is related to dietary supplementation with prebiotics, probiotics, and phytogenic substances. These supplements exert their effects indirectly through manipulation of gut microbiota quality and improvement in intestinal epithelial barrier. Several phytogenic substances, such as berberine, resveratrol, curcumin, carvacrol, thymol, isoflavones and hydrolyzed fibers, have been identified as potential supplements that may also act as welcome means to reduce the usage of antibiotics in feedstock, including poultry farming, through manipulation of the gut microbiome. In addition, these compounds may improve the integrity of tight junctions by controlling tight junction-related proteins and inflammatory signaling pathways in the host animals. In this review, we discuss the role of probiotics, prebiotics, and phytogenic substances in optimizing gut function in poultry.

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“…Many studies report immunomodulatory and health benefits for SCFP applications in monogastric and ruminant mammalian species as well as in chicken [1,2]. The mechanisms of action of SCFP are manifold and include direct interaction of pre-and postbiotic ingredients with local gut epithelial [3,4] and immune [5] cells, as well as the modulation of gut microbiota composition [6,7]. However, immunomodulatory effects of SCFP are not restricted to the gut.…”

Section: Introductionmentioning

confidence: 99%

A Saccharomyces cerevisiae Fermentation Product (Olimond BB) Alters the Early Response after Influenza Vaccination in Racehorses

Lucassen

Finkler-Schade²,

Schuberth

2021

Animals

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Saccharomyces cerevisiae (S. cerevisiae) fermentation products (SCFP) are used in animal husbandry as pre- and postbiotic feed supplements. A variety of immunomodulatory effects are noted in many species. The purpose of this study was to test the hypothesis that horses fed with SCFP containing feed additive Olimond BB display a modulated early immune response after influenza vaccination. Six horses received Olimond BB pellets (OLI) and five horses were fed placebo pellets (PLA) for 56 days. On day 40 all horses were vaccinated with a recombinant influenza A/equi-2 vaccine. At the day of vaccination, the groups did not differ in the composition of leukocyte subpopulations and reticulocytes. Twenty-four hours after vaccination total leukocyte counts and numbers of CD4+ T-cells significantly increased in both groups. In PLA horses, the numbers of neutrophil granulocytes significantly increased and numbers of CD8+ T-cells decreased, whereas the numbers of these cell types remained unchanged in OLI horses. Only OLI horses displayed a significant increase in reticulocyte percentages after vaccination. The numbers of lymphocytes, monocytes, CD21+ B-cells, and serum amyloid A levels remained unaffected in both groups after vaccination. Sixteen days after vaccination, PLA and OLI horses differed significantly in their enhanced ELISA IgG titres against Newmarket and Florida Clade 1 influenza strains. The observed differences after vaccination suggest that feed supplementation with Olimond BB leads to modulated early immune responses after influenza vaccination, which may also affect the memory responses after booster vaccination.

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Nutraceuticals

Cited by 32 publications

References 97 publications

Effects of feeding CLOSTAT (Bacillus subtilis PB6) on the clinical health, performance, and carcass characteristics of feedlot steers1

Effects of feeding CLOSTAT (Bacillus subtilis PB6) on the clinical health, performance, and carcass characteristics of feedlot steers1

Probiotics, Prebiotics, and Phytogenic Substances for Optimizing Gut Health in Poultry

A Saccharomyces cerevisiae Fermentation Product (Olimond BB) Alters the Early Response after Influenza Vaccination in Racehorses

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