Nutraceuticals for Fertility and Erectile Health: A Brief Overview of What Works and What Is Worthless

Moyad, Mark A.

doi:10.1007/978-1-4939-0425-9_12

Cited by 2 publications

(2 citation statements)

References 212 publications

(218 reference statements)

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“…On the other hand, vitamin C can be metabolized to oxalate and might increase kidney oxalate excretion. Several studies suggest that vitamin C supplements may increase urinary oxalate concentrations, doubling the risk of calcium oxalate kidney stones [25,26,27]. A study defined that high vitamin C intake from supplements is associated with a rise in cardiovascular disease mortality in postmenopausal women with diabetes but this has never been confirmed [28].…”

Section: Adverse Effects Of Antioxidantsmentioning

confidence: 99%

Antioxidants: Positive or Negative Actors?

et al. 2018

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The term “antioxidant” is one of the most confusing definitions in biological/medical sciences. In chemistry, “antioxidant” is simply conceived “a compound that removes reactive species, mainly those oxygen-derived”, while in a cell context, the conceptual definition of an antioxidant is poorly understood. Indeed, non-clinically recommended antioxidants are often consumed in large amounts by the global population, based on the belief that cancer, inflammation and degenerative diseases are triggered by high oxygen levels (or reactive oxygen species) and that through blocking reactive species production, organic unbalances/disorders can be prevented and/or even treated. The popularity of these chemicals arises in part from the widespread public mistrust of allopathic medicine. In fact, reactive oxygen species play a dual role in dealing with different disorders, since they may contribute to disease onset and/or progression but may also play a key role in disease prevention. Further, the ability of the most commonly used supplements, such as vitamins C, E, selenium, and herbal supplements to decrease pathologic reactive oxygen species is not clearly established. Hence, the present review aims to provide a nuanced understanding of where current knowledge is and where it should go.

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Section: Adverse Effects Of Antioxidantsmentioning

confidence: 99%

Antioxidants: Positive or Negative Actors?

et al. 2018

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“…The more recent link between nutrition and skin aging began in earnest around the year 2000 with the demonstrated increase in peer-reviewed scientific journal reports on this topic [ 12 ]. Thus, the application of: (a) topical administration from outside to inside the skin and (b) the inside by oral consumption of nutritionals to the outer skin layers is now common place and many journal reports exhibit significant improvement for both on a variety of dermal parameters [ 11 , 13 , 14 , 15 , 16 , 17 ]. This review covers, where applicable, the history, chemical structure and sources, biological and biomedical properties in the skin, and, lastly, animal and clinical data on the oral applications of: (a) collagen, (b) ceramide, (c) β-carotene, (d) astaxanthin, (e) coenzyme Q 10 , (f) colostrum, (g) zinc, and (h) selenium in their mode of action or function in improving skin health and various dermal endpoints.…”

Section: Introductionmentioning

confidence: 99%

Enhancing Skin Health: By Oral Administration of Natural Compounds and Minerals with Implications to the Dermal Microbiome

Vollmer¹,

West²,

Lephart

2018

IJMS

102

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The history of cosmetics goes back to early Egyptian times for hygiene and health benefits while the history of topical applications that provide a medicinal treatment to combat dermal aging is relatively new. For example, the term cosmeceutical was first coined by Albert Kligman in 1984 to describe topical products that afford both cosmetic and therapeutic benefits. However, beauty comes from the inside. Therefore, for some time scientists have considered how nutrition reflects healthy skin and the aging process. The more recent link between nutrition and skin aging began in earnest around the year 2000 with the demonstrated increase in peer-reviewed scientific journal reports on this topic that included biochemical and molecular mechanisms of action. Thus, the application of: (a) topical administration from outside into the skin and (b) inside by oral consumption of nutritionals to the outer skin layers is now common place and many journal reports exhibit significant improvement for both on a variety of dermal parameters. Therefore, this review covers, where applicable, the history, chemical structure, and sources such as biological and biomedical properties in the skin along with animal and clinical data on the oral applications of: (a) collagen, (b) ceramide, (c) β-carotene, (d) astaxanthin, (e) coenzyme Q10, (f) colostrum, (g) zinc, and (h) selenium in their mode of action or function in improving dermal health by various quantified endpoints. Lastly, the importance of the human skin microbiome is briefly discussed in reference to the genomics, measurement, and factors influencing its expression and how it may alter the immune system, various dermal disorders, and potentially be involved in chemoprevention.

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Nutraceuticals for Fertility and Erectile Health: A Brief Overview of What Works and What Is Worthless

Cited by 2 publications

References 212 publications

Antioxidants: Positive or Negative Actors?

Antioxidants: Positive or Negative Actors?

Enhancing Skin Health: By Oral Administration of Natural Compounds and Minerals with Implications to the Dermal Microbiome

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