Nutrigenomics and polyphenols

Plant adaptive strategies have been shaped during evolutionary development in the constant interaction with a plethora of environmental factors, including the presence of metals/metalloids in the environment. Among adaptive reactions against either the excess of trace elements or toxic doses of non-essential elements, their complexation with molecular endogenous ligands, including phenolics, has received increasing attention. Currently, the complexation of phenolics with metal(loid)s is a topic of intensive studies in different scientific fields. In spite of the numerous studies on their chelating capacity, the systemic analysis of phenolics as plant ligands has not been performed yet. Such a systematizing can be performed based on the modern approach of metallomics as an integral biometal science, which in turn has been differentiated into subgroups according to the nature of the bioligands. In this regard, the present review summarizes phenolics–metal(loid)s’ interactions using the metallomic approach. Experimental results on the chelating activity of representative compounds from different phenolic subgroups in vitro and in vivo are systematized. General properties of phenolic ligands and specific properties of anthocyanins are revealed. The novel concept of metallophenolomics is proposed, as a ligand-oriented subgroup of metallomics, which is an integrated approach to study phenolics–metal(loid)s’ complexations. The research subjects of metallophenolomics are outlined according to the methodology of metallomic studies, including mission-oriented biometal sciences (environmental sciences, food sciences and nutrition, medicine, cosmetology, coloration technologies, chemical sciences, material sciences, solar cell sciences). Metallophenolomics opens new prospects to unite multidisciplinary investigations of phenolic–metal(loid) interactions.

show abstract

The Role of Phytogenic Feed Additives in Modulating Poultry Nutritional Physiology and Genomics

İpçak¹

2023

Veterinary Medicine and Science

View full text Add to dashboard Cite

In this chapter, the effects of phytogenic feed additives (PFAs) on the performance, intestinal health, microbiota, oxidative stress, antioxidant defense system, gene expression, and protein production of poultry were examined. PFAs consist of plant-derived components such as essential oils, flavonoids, saponins, phenolic compounds, and alkaloids. They have gained increasing popularity in recent years as alternative growth-promoting products to antibiotics used for animal nutrition. Studies have indicated that PFAs positively affect the overall health and productivity of poultry. Indeed, it has been observed that the use of PFAs in poultry nutrition enhances performance, modifies intestinal microbiota and morphology, and modulates gene expression and protein synthesis. Thus, the use of PFAs in poultry farming is an important alternative to increasing productivity and transitioning to a more sustainable and natural production system. However, further research is needed to understand the efficacy and safety of PFAs, interactions between different phytogenic components, and their synergistic effects. Furthermore, determining the appropriate levels and application methods is crucial to guide producers and reach a wider audience in poultry farming. In conclusion, supporting the use of phytogenic feed additives within the framework of legal regulations and standards is important for the sustainability of the industry and health of consumers.

show abstract

Nutrigenomics and polyphenols

Cited by 3 publications

References 100 publications

A multi-omics approach to understand the influence of polyphenols in ovarian cancer for precision nutrition: a mini-review

A multi-omics approach to understand the influence of polyphenols in ovarian cancer for precision nutrition: a mini-review

Metallophenolomics: A Novel Integrated Approach to Study Complexation of Plant Phenolics with Metal/Metalloid Ions

The Role of Phytogenic Feed Additives in Modulating Poultry Nutritional Physiology and Genomics

Contact Info

Product

Resources

About