Nutrition and Diet in Rheumatoid Arthritis

Cutolo, Maurizio; Nikiphorou, Elena

doi:10.3390/nu14040888

Cited by 13 publications

(10 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Some authors postulate that the microbiota and the intestinal barrier may be a missing link between the various nutritional factors and the development of RA. The modification of microbiota using dietary interventions and focusing on the improvement of the intestinal barrier function may become an important component for "preventive" nutritional strategies (77). Not only in RA but also in primary Sjögren's syndrome researchers gave attention to bacteria and microbiome in pathogenesis and severity of the disease: it is possible that distorted immune response to a normal microbiota, rather than specific infections, may be a first step in the pathogenesis of pSS.…”

Section: Diet and Microbiomementioning

confidence: 99%

Environment and arthritis

Ruzzon,

Adami

2024

Clinical and Experimental Rheumatology

View full text Add to dashboard Cite

The present narrative review explores the multifactorial aetiology of rheumatoid arthritis (RA) and other immunemediated inflammatory disorders (IMI-Ds), emphasising the significant role of various environmental factors in disease development and exacerbation. Key modifiable environmental factors such as cigarette smoking and air pollution are identified as major contributors to RA. We will also focus on the influence of weather, seasonality, and particularly vitamin D levels, on RA activity, suggesting potential for seasonal management and supplementation to mitigate disease severity. The emerging role of diet and the gut microbiome in RA pathogenesis and progression is discussed as well, with dietary interventions and specific nutrients like omega-3 fatty acids offering protective benefits against inflammation. Despite the mounting evidence around these factors, further research is needed, to better understand the clinical impacts on RA, including well-designed randomised clinical trials.

show abstract

Section: Diet and Microbiomementioning

confidence: 99%

Environment and arthritis

Ruzzon,

Adami

2024

Clinical and Experimental Rheumatology

View full text Add to dashboard Cite

show abstract

“…Forscher*innen in der Rheumatologie hingegen nahmen bislang Fettsäure-Strukturen in den primären Fokus [9,10,11]. Fettsäuren (und damit ihre Qualität) und ihr Einfluss auf das Entzündungsgeschehen werden gefühlt häufiger diskutiert als die Fettportion selbst.…”

Section: Makronährstoffe Im Blickunclassified

“…Die mediterrane Ernährung wird in den vergangenen Jahren sowohl für Menschen mit Diabetes als auch für Rheumatiker*innen offiziell empfohlen [5,9,10,11]. (z.…”

Section: Mediterrane Ernährungdie Lösung?unclassified

Antientzündliche Ernährung und Lebensmittel für das Immunsystem

Blumenschein

2023

Diabetes aktuell

View full text Add to dashboard Cite

show abstract

“…A plethora of genetic and environmental factors have been implicated in the pathogenesis of RA, with diet quality playing a significant role in the development of the entity, its pathophysiology, the manifestation of symptoms, and the management of RA [ 7 , 8 , 9 ]. Various dietary patterns, including the Mediterranean diet (MD), and individual nutrients including certain types of fatty acids and vitamin D, have been investigated for their potential associations with the development and prognosis of RA [ 10 , 11 , 12 , 13 , 14 ].…”

Section: Introductionmentioning

confidence: 99%

Mediterranean Diet and Physical Activity Nudges versus Usual Care in Women with Rheumatoid Arthritis: Results from the MADEIRA Randomized Controlled Trial

Παπανδρέου

Gioxari

Daskalou³

et al. 2023

Nutrients

View full text Add to dashboard Cite

In rheumatoid arthritis (RA), diet quality and nutritional status have been shown to impact the disease activity and adherence to the Mediterranean diet (MD) has been suggested as an anti-inflammatory regime to improve disease status and reduce cardiovascular risk. The Mediterranean DiEt In Rheumatoid Arthritis (MADEIRA) was a single-blind (statistician), two-arm randomized clinical trial, investigating the effects of a 12-week lifestyle intervention, including a personalized isocaloric MD plan with the promotion of physical activity (PA), supported through a clinical decision support systems (CDSS) platform, versus usual care in women with RA. Forty adult women with RA on remission were randomly allocated (1:1 ratio) to either the intervention or the control arm. The intervention group received personalized MD plans and lifestyle consultation on improving PA levels, whereas the controls were given generic dietary and PA advice, based on the National Dietary Guidelines. The primary outcome was that the difference in the MD adherence and secondary outcomes included change in disease activity (DAS28), anthropometric indices (BodPod), dietary intake, PA, vitamin D concentrations, and blood lipid profiles after 12 weeks from the initiation of the trial. At 3 months post-baseline, participants in the MD arm exhibited greater adherence to the MD compared with the controls (p < 0.001), lower DAS28 (p < 0.001), favorable improvements in dietary intake (p = 0.001), PA (p = 0.002), body weight and body composition (p < 0.001), blood glucose (p = 0.005), and serum 1,25(OH)2D concentrations (p < 0.001). The delivery of the MD and PA promotion through CDSS nudges in women with RA in an intensive manner improves the MD adherence and is associated with beneficial results regarding disease activity and cardiometabolic-related outcomes, compared with the usual care.

show abstract

Nutrition and Diet in Rheumatoid Arthritis

Abstract: Rheumatic and musculoskeletal diseases (RMDs) are chronic systemic immune/inflammatory conditions characterized by the interaction between gene predisposition, autoimmunity and environmental factors [...]

Cited by 13 publications

References 16 publications

Environment and arthritis

Environment and arthritis

Antientzündliche Ernährung und Lebensmittel für das Immunsystem

Mediterranean Diet and Physical Activity Nudges versus Usual Care in Women with Rheumatoid Arthritis: Results from the MADEIRA Randomized Controlled Trial

Contact Info

Product

Resources

About