Nutrition for Aging Cats and Dogs and the Importance of Body Condition

Laflamme, Dorothy P.

doi:10.1016/j.cvsm.2004.12.011

Cited by 111 publications

(91 citation statements)

References 106 publications

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“…All had a body condition score of 7 or 8 on the 9-point scale (25) . They were housed at the National Veterinary School of Nantes according to the regulations for animal welfare of the French Ministry of Agriculture and Fisheries.…”

Section: Animals and Dietmentioning

confidence: 99%

Effects of green tea on insulin sensitivity, lipid profile and expression of PPARα and PPARγ and their target genes in obese dogs

et al. 2008

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As in man, canine obesity is associated with insulin resistance, dyslipidaemia and other chronic diseases. This study was designed to examine the effects of a nutritional supplement (green tea) on insulin sensitivity and plasma lipid concentrations in an obese insulin-resistant dog model. We also determined mRNA expression of two transcription factors, PPARg and PPARa, and some of their target genes, including GLUT4, lipoprotein lipase (LPL) and adiponectin. Obese dogs were divided into two groups: a green tea group (n 6); a control group (n 4). Dogs in the green tea group were given green tea extract (80 mg/kg per d) orally, just before their single daily meal, for 12 weeks. Insulin sensitivity (using a euglycaemic -hyperinsulinaemic clamp) and concentrations of plasma TAG, total cholesterol and NEFA were assessed in each group. Gene expression was measured in visceral and subcutaneous adipose tissues and in liver and skeletal muscle, by real-time PCR. At 12 weeks in the green tea group, mean insulin sensitivity index was 60 (SEM 11) % higher (P,0·05) and TAG concentration 50 (SEM 10) % lower (P,0·001), than baseline. PPARg, GLUT4, LPL and adiponectin expression were significantly higher in both adipose tissues, whilst PPARa and LPL expression were significantly higher in skeletal muscle, compared with baseline. These findings show that nutritional doses of green tea extract may improve insulin sensitivity and lipid profile and alter the expression of genes involved in glucose and lipid homeostasis.

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Section: Animals and Dietmentioning

confidence: 99%

Effects of green tea on insulin sensitivity, lipid profile and expression of PPARα and PPARγ and their target genes in obese dogs

et al. 2008

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“…48,58 This increased protein requirement does not seem to be an effect of decreased digestibility; in fact, as discussed earlier, several studies support a static or increased digestive efficiency for protein. 19,21 However, there is an age-related decline in protein synthesis 59 and increased protein turnover in older animals.…”

Section: Proteinmentioning

confidence: 78%

“…62,63 Because older pets have a higher requirement for dietary protein, a reduction in intake further widens the gap between need and provision and is likely to be even more detrimental than in younger animals. 48 In addition, if caloric intake is decreased to manage weight gain, the proportion of energy provided as protein should be increased. 48,64 Phosphorus Although phosphorus restriction has been shown to slow progression of disease in dogs with CKD, 65 there is no evidence that this is effective in the prevention of the development of CKD.…”

Section: Proteinmentioning

confidence: 99%

“…48 In addition, if caloric intake is decreased to manage weight gain, the proportion of energy provided as protein should be increased. 48,64 Phosphorus Although phosphorus restriction has been shown to slow progression of disease in dogs with CKD, 65 there is no evidence that this is effective in the prevention of the development of CKD. Restriction is not warranted unless and until CKD is documented, which underscores the importance of regular screening and assessment of dogs for risk factors for CKD as well as other diseases.…”

Section: Proteinmentioning

confidence: 99%

“…[42][43][44] The magnitude of the decrease has been reported to be approximately 20% 20,44-46 but may range up to 50%. 47 One reason for the decline is associated with an age-related decline in lean body mass (LBM) 48 because the primary driver of resting energy requirement is LBM, 49 and LBM declines with age 50 with a concurrent increase in body fat mass. [51][52][53] However, other causes may also be involved, as decreased lean body mass has not been noted in all cases of older dogs with decreased maintenance energy requirement.…”

Section: Energymentioning

confidence: 99%

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