Artificial nutrition support in hospital: indications and complications
Malnutrition is a common clinical problem in hospitalised patients and is both a cause and consequence of diseaseArtificial nutrition support with enteral or parenteral nutrition is indicated in patients who are malnourished or at risk of malnutrition where food fortification and/or oral nutritional supplements are inadequate Enteral tube feeding should be used in preference to parenteral nutrition where the gastrointestinal tract is functioning adequately; if there is doubt, enteral and parenteral feeding can temporarily be used in combination
Enteral tube insertionProblems arising shortly after insertion of enteral tubes should arouse suspicion of an insertion complication. Such complications can be minimised by ensuring that correct placement procedures are followed by trained healthcare professionals. Nasogastric tube positioning should be confirmed with a tube aspirate pH<5. If there is any doubt about tube positioning, the patient is on acid suppression or a naso-jejunal tube has been inserted, an X-ray is needed to exclude bronchial placement. Injection of air through the tube and auscultation with a stethoscope is unreliable and should not be used. 11 To minimise the risks of pulmonary aspiration, patients should be fed propped up by 30°or more and kept propped up for 30 minutes after feeding. 11
Venous catheterisationProblems arising shortly after insertion of a venous catheter (frequently a central venous catheter) for parenteral nutrition should also arouse suspicion of an insertion complication (eg shortness of breath due to pneumothorax, blockage of line due to kinking of catheter). Meticulous care in inserting catheters under aseptic conditions by trained operators can do much to minimise the risk of these complications.
Catheter-related sepsisCatheter-related sepsis is a major complication, the causes of which frequently relate to inappropriate procedures and techniques, for example multiple blood sampling and inadequate aseptic technique when inserting and accessing lines. If line sepsis is suspected, parenteral feeding should be stopped and blood cultured both from peripheral and central line sites prior to initiating antibiotics. Temporary lines should usually be removed, although in minor catheterrelated sepsis due to Staphylococcus
Metabolic disturbancesMetabolic disturbances occur with both enteral and parenteral nutrition support, although they are more common with the latter as many of the body's homeostatic mechanisms are overridden. Hyperglycaemia is common, particularly in the critically ill who have coexisting insulin resistance which predisposes to septic complications. A raised blood glucose of a few mmol/l may have major deleterious effects on clinical outcome in critical illness in both medical and surgical patients. 8,12,13 These patients should be monitored closely, with careful consideration of feeding levels and a low threshold for introducing insulin therapy.
Refeeding syndromeMalnourished patients who ...