Nutrition in Renal Disease

Druml, Wilfred

doi:10.1007/978-1-4613-1859-0_13

Cited by 1 publication

(2 citation statements)

References 109 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Im proved organ function is also apparent be cause a low protein diet supplemented with EAAs can correct the abnormally low resting potential of muscle membranes that occurs in patients with advanced uremia [46], One metabolic product that may be neph rotoxic is oxalate. CRF causes secondary hyperoxalemia and progressive deposition of oxalate within the kidney, interstitial nephri tis and, potentially, progressive renal insuffi ciency [47,48], Although the pathologic im portance of oxalate is undetermined, reduc ing dietary protein and hence the intake of oxalate precursors (e.g., glycine) decreases serum oxalate in CRF patients [49]. In fact, S o and oxalate concentrations are correlated in patients eating an unrestricted diet.…”

Section: Reduction O F Uremic Toxicitymentioning

confidence: 99%

“…Renal cal cium content increases as renal failure ad vances, but tissue calcification is dependent on the calcium-phosphate product which is raised by renal failure. In rats, there is evidence for and against an important role of excess phos phorus in the progression of renal failure [4,48,51]. In humans, the rate progression of CRF has been shown to be correlated with the amount of urinary phosphorus [52].…”

Section: Amelioration O F Secondary Hyperparathyroidism and Abnormal mentioning

confidence: 99%

See 1 more Smart Citation

Protein-Restricted Diets and Progression of Renal Failure

Druml

1988

Blood Purif

Self Cite

View full text Add to dashboard Cite

Interest in dietary therapy of chronic uremia has reawakened because such therapy may slow or halt progression of renal insufficiency. The efficacies of three regimens: 0.6 g protein/kg/day; 0.3 g protein/kg/day plus essential amino acids, and 0.3 g protein/kg/day plus keto acid regimens, have been tested. Each can maintain nitrogen balance if properly administered but if dietary protein and/or the supplement are inadequate, muscle wasting will occur. Data showing that each can slow the rise in serum creatinine are presented. The problems with using serum creatinine, potential mechanisms for the effect on progression and methods for monitoring compliance are discussed.

show abstract