Nutrition Intake and Nutrition Status of Pancreatic Cancer Patients: Cross-Sectional and Longitudinal Analysis of a Randomized Controlled Exercise Intervention Study

Steindorf, Karen; Clauss, Dorothea; Rötzer, Ingeborg; Tjaden, Christine; Hackert, Thilo; Wiskemann, Joachim

doi:10.1080/01635581.2022.2077382

Cited by 4 publications

(6 citation statements)

References 30 publications

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“…Studies such as Clauss et al [12] observed that a low protein intake (being <1.0 g/kg of body weight/day) was found in one-third of the study sample (20 patients diagnosed with pancreatic cancer), the majority being patients at risk of malnutrition. In contrast, a recent systematic review assessed whether high protein intake should be considered for cancer patients undergoing treatment [8].…”

Section: Therapeutic Conduct For Proteins In Cancermentioning

confidence: 88%

“…Still, it is not clear what the protein recommendation is in relation to the different phases of oncological treatment and what would be the ideal period of this recommendation to favor clinically positive results [3,5,9,10,11 && ]. Studies such as Clauss et al [12] observed that a low protein intake (being <1.0 g/kg of body weight/ day) was found in one-third of the study sample (20 patients diagnosed with pancreatic cancer), the majority being patients at risk of malnutrition. In contrast, a recent systematic review assessed whether high protein intake should be considered for cancer patients undergoing treatment [8].…”

Section: Creatine Supplementation To Clinically Treat Cancer Patients...mentioning

confidence: 88%

“…In addition, patients at risk or diagnosed with malnutrition should be prescribed diets with an upper protein limit to recover and maintain muscle function. Finally, the author also suggests combining nutritional therapy with physical activity for better results [12].…”

Section: Therapeutic Conduct For Proteins In Cancermentioning

confidence: 99%

“…In addition to fragility, guidelines seem to centralize the nutritional approach during periods of exacerbation of the inflammatory process. In periods when this does not occur, the high protein recommendation seems uncertain [4 ▪▪ ,9,10,11 ▪▪ ,12].…”

Section: Therapeutic Conduct For Proteins In Cancermentioning

confidence: 99%

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Amino acids and cancer: potential for therapies?

Siqueira,

Vega,

Pimentel

2023

Current Opinion in Clinical Nutrition &Amp; Metabolic Care

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Purpose of review Cancer patients may have a variety of disorders associated with systemic inflammation caused by disease progression. Consequently, we have protein hypercatabolism. In view of this, protein and amino acid adequacy should be considered in relation to nutritional behavior. Therefore, this review aims to evaluate the influence of protein and amino acids in the nutritional therapy of cancer. Recent findings Diets with adequate protein levels appear to be beneficial in the treatment of cancer; guidelines suggest consumption of greater than 1.0–1.5 g/kg body weight/day. In patients diagnosed with malnutrition, sarcopenia, or cachexia, it is recommended to use the maximum amount of protein (1.5 g/kg of weight/day) to adapt the diet. In addition, based on the evidence found, there is no consensus on the dose and effects in cancer patients of amino acids such as branched-chain amino acids, glutamine, arginine, and creatine. Summary When evaluating the components of the diet of cancer patients, the protein recommendation should be greater than 1.0–1.5 g/kg of weight/day, with a distribution between animal and vegetable proteins. We found little evidence demonstrating clinical benefits regarding individual or combined amino acid supplementation. Still, it is unclear how the use, dose, and specificity for different types of cancer should be prescribed or at what stage of treatment amino acids should be prescribed.

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Section: Therapeutic Conduct For Proteins In Cancermentioning

confidence: 88%

Section: Creatine Supplementation To Clinically Treat Cancer Patients...mentioning

confidence: 88%

Section: Therapeutic Conduct For Proteins In Cancermentioning

confidence: 99%

Section: Therapeutic Conduct For Proteins In Cancermentioning

confidence: 99%

See 2 more Smart Citations

Amino acids and cancer: potential for therapies?

Siqueira,

Vega,

Pimentel

2023

Current Opinion in Clinical Nutrition &Amp; Metabolic Care

View full text Add to dashboard Cite

show abstract

“…However, the presence of cancer is not necessarily associated with a poor protein intake. When studying pancreatic cancer patients, Steindorf et al reported that a low protein intake (i.e., <1.0 g/kg BW/day) is detectable in approximately one-third of the sample mostly overlapping those at risk of malnutrition and those also not meeting caloric requirements [10]. The cumulated evidence suggests that high protein diets as defined by an intake >1.0 g/kg BW/day are key to maintain an adequate nutritional status in patients with cancer and represent a valid target to meet by those patients at nutritional risk.…”

Section: Recommended Daily Protein Intake and Adequacy In Patients Wi...mentioning

confidence: 99%

High protein diet in digestive cancers

Laviano¹

2022

Current Opinion in Clinical Nutrition &Amp; Metabolic Care

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Purpose of reviewRecent advances in the nutritional management of patients with digestive cancers suggest that modulation of protein intake may significantly contribute to achieve nutritional and clinical benefits. By reviewing the available evidence, a quantitatively and qualitatively optimal protein intake could be derived.Recent findingsHigh protein diets (i.e., 1–1.5 g/kg body weight/day) appear key to maintain the adequate nutritional status, and may also contribute to achieve clinical benefits. This target appears particularly relevant in patients with digestive cancers at risk or already malnourished, or in older patients. During active cancer treatments, protein intake should be closer to the upper limit of the recommended intake. Also, high protein intake should be maintained beyond the periods of catabolic crisis associated with active treatments. In contrast with general reasoning, animal proteins should represent the majority of the recommended intake. Based on the available evidence, the intake of no specific amino acid can be strongly recommended to enhance anabolic potentials or the immune modulating effects of high protein diets.SummaryHigh protein intake, mostly based on animal proteins, should be recommended to patients with digestive cancers. However, this target should be translated into clinical prescription after considering the clinical and metabolic needs of the patients. The quest for the optimal protein intake of patients with cancer at different time points of their clinical journey is still open.

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Multifunctional Cadmium-Based Metal–Organic Frameworks for the Detection of Ion and Molecule in Aqueous Media

Zhang,

He,

Zhang

et al. 2024

Crystal Growth & Design

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The development of materials capable of simultaneously detecting multiple analytes has been a significant challenge. This paper presents the synthesis of two novel Cd-MOFs, namely CUST-781 and CUST-782 (CUST = Changchun University of Science and Technology), using a solvothermal synthesis method. CUST-781 and CUST-782 were carefully characterized. CUST-781 and CUST-782 are both two-dimensional supramolecular structures formed through hydrogen bonding. Luminescence sensing studies demonstrate that CUST-781 can sensitively detect lower concentrations of Fe3+, 2,4,6-trinitrophenol (TNP), and the antibiotic ceftriaxone sodium. Similarly, CUST-782 shows fluorescence quenching in response to Fe3+, Cr2O7 2–, TNP, and the antibiotic tetracycline. The possible mechanisms of fluorescence quenching were investigated in detail. It can be inferred that CUST-781 and CUST-782 serve as fluorescent probes to provide a new strategy for directly detecting harmful substances in aqueous solution.

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Nutrition Intake and Nutrition Status of Pancreatic Cancer Patients: Cross-Sectional and Longitudinal Analysis of a Randomized Controlled Exercise Intervention Study

Cited by 4 publications

References 30 publications

Amino acids and cancer: potential for therapies?

Amino acids and cancer: potential for therapies?

High protein diet in digestive cancers

Multifunctional Cadmium-Based Metal–Organic Frameworks for the Detection of Ion and Molecule in Aqueous Media

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