Nutritional benefits, ethnomedicinal uses, phytochemistry, pharmacological properties and toxicity of Spondias mombin Linn: a comprehensive review

Abstract

Objectives Spondias mombin is traditionally used as an herbal medicine for several human diseases and ailments in the tropical regions across the globe including the African countries. This study aimed to provide comprehensive information on nutritional benefits, ethnomedicinal uses, phytochemical constituents, pharmacological properties and toxicology study of S. mombin. Information was gathered from documented literatures in scientific database. Key findings The study revealed that S. mombin has nutritional values; with the leaf, fruit, flower, seed, and stem bark possessing a wide range of ethnomedicinal uses across several regions, with documented pharmacological properties. S. mombin has a frequent rate of ethnomedicinal utility in cases of abortion, constipation, fever, gonorrhea, postpartum hemorrhage, digestive pain, diarrhoea, dysentery and wounds. Ethnopharmacological studies showed that crude extracts and chemical compounds from S. mombin manifested in vivo and in vitro biological and pharmacological activities. About 102 isolated compounds from the leaf, fruit, or stem bark of S. mombin have been reported. Summary Overall, S. mombin has several nutritive and ethnomedicinal benefits owing to its chemical constituents, which are linkable to the several pharmacological activities. There remains however, the need for dosage intake caution, upon the advice of medical professionals.

Studies of the Indigenous Edible Wild Fruits of Etche Local Government Area, Rivers State, Nigeria

“…It was observed that some of the IEWFs have diverse alternative uses other than the edibility of the fruits. Olalekun et al (2003) documented that S. mombin fruits have various uses, its fruits are usually consumed fresh or processed and are generally accepted for their unique sweet-sour taste. The same fruits are used to treat angina, stomach ulcer, vaginal and uterine disorder; the squeezed fruit juice is taken as heart tonic in Brazil.…”

Spondias tuberosa and Spondias mombin: Nutritional Composition, Bioactive Compounds, Biological Activity and Technological Applications

“…From 2019, there was a substantial increase in publication numbers followed by 2020 and 2021. The areas of knowledge are mainly distributed among biotechnology applied microbiology (33), pharmacology/pharmacy (32), food science and technology (21), and polymer science (17). Some applications are focused on the preparation of functional food and beverages, extraction and isolating active substances such as flavonoids and other phenolic compounds, as well as pharmaceutical and cosmetic formulations.…”

“…However, they do not bring together, in the same work, information about S. tuberosa and S. mombin, unlike this review, which brings together information about academic research and patents relating to the two fruits. Also, a bibliometric analysis of articles published in the last 20 years is provided herein; these characteristics differ this review from others that are already published [25][26][27][28][29][30][31][32][33].…”

Phytopharmacological Activities of Spondias mombinLinn: A Review

“…7,[9][10][11] It is a medicinal plant that has wide acceptability and proven to exert certain beneficial health activities which include antiepileptic, antidementia, antipsychotic, anticancer, cytotoxic, anthelmintic, antiviral, and anxiolytic pharmacological activities. [12][13][14][15]…”