Nutritional fat modulation as a non-pharmacological approach to children infected with COVID-19, a challenge in food biochemistry.

Atef, Hoda

doi:10.21608/ejchem.2021.87893.4234

Cited by 4 publications

(3 citation statements)

References 32 publications

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“…Obesity should be recruited as individual risk factors for higher COVID-19 severity and mortality outcomes [58]. Obesity is a well-known risk factor for acquiring COVID-19 and infections in general [59]. The regulated expression of miRNAs (microRNA) is crucial in the immunomodulation and more than 23 circulating miRNAs are deregulated in obese individuals.…”

Section: Discussionmentioning

confidence: 99%

Biochemical and Anthropometric Nutritional Assessment in Children Infected with COVID-19: A Cross-sectional Study

Ibrahim

Helmy

Amin

et al. 2022

Open Access Maced J Med Sci

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Background: Severe acute respiratory syndrome has led to a pandemic of coronavirus disease 2019 (COVID-19). Malnutrition either biochemically or anthropometrically is a well-known risk factor for COVID-19 and may be the vice versa Objectives : To investigate the prevalence of malnutrition in children infected with COVID-19 through evaluating the nutritional biomarkers such as serum electrolytes, serum albumin and hemoglobin together with the anthropometric assessment. Methods: A cross sectional study that was conducted at ElMatria Teaching Hospital for all children admitted with confirmed COVID-19 over a period of 6 months from 1st February 2021 to the end of July, 2021. Nutritional biochemical evaluation included serum electrolytes particularly the potassium and other nutritional biomarkers such as serum albumin and hemoglobin. Nutritional anthropometric evaluation depended on BMI (body mass index), the height/length, weight for length and weight for height..The prevalence of malnutrition esp. hypokalemia was the main outcome. Results: Hypokalemia was present in 21.8% of the study participants . Other nutritional biomarkers were found as hyponatremia, hypocalcemia , hypophosphatemia, hypomagnesemia were detected in 49.1% , 38.2%,21.8% and 34.5% of the study subjects respectively. Anthropometric malnutrition was present in most of the enrolled children with COVID-19 in the study (65.5 % (n= 36) )through which overweight and obese children occupied a greater percentage. Conclusion: Malnutrition either biochemically or anthropometrically could be linked to COVID-19 in children. COVID-19 could have negative outcomes on the nutritional status such as electrolytes disturbances. Both malnutrition and COVID-19 are considered synergistic associations Keywords: Malnutrition. COVID-19. Children. Hypokalemia. Obesity

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Section: Discussionmentioning

confidence: 99%

Biochemical and Anthropometric Nutritional Assessment in Children Infected with COVID-19: A Cross-sectional Study

Ibrahim

Helmy

Amin

et al. 2022

Open Access Maced J Med Sci

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“…On March 2020, the Coronavirus disease of 2019 (COVID- 19) was declared by the World Health Organization (WHO) as a pandemic (1) . A worldwide regular attempt is needed to prevent the more unfold of the virus.…”

Section: Introductionmentioning

confidence: 99%

Acid-Base Disturbances in Pediatrics Infected With COVID-19, A Cross Sectional Study

Ibrahim¹,

Mostafa²,

Helmy³

et al. 2023

The Egyptian Journal of Hospital Medicine

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Background: Data on the pathophysiology and clinical spectrum of COVID-19 in children are few. The dominant respiratory outcome of COVID-19 is arterial hypoxaemia. Arterial Blood Gas (ABG) analysis helps detect early acid base balance alternations. Acid-base imbalance hasn't been outlined well in children with COVID-19. Objective: The aim of the current study is to evaluate the blood gas levels as a reflection to the acid-base status among COVID19 children at admission and to detect the pattern of acid-base disorders. Patients and methods: A total of 62 children with positive nasopharyngeal swabs were assessed for ABG at the time of admission in ElMatria Teaching Hospital from February 1, 2021 to the end of July 2021. Results: Among the study subjects, 53% were males and 47% were female. Most affected age group was <2 years. 53% presented by GIT manifestation (fever, nausea, vomiting, diarrhea), 37% presented by respiratory manifestation (fever, cough, dyspnea). Most common ABG finding was hypoxemia in 90.3% (P<0.001). PH (potential hydrogen) of about 50% was within the normal range, while 37.1% had acidosis and 12.9% had alkalosis (P<0.001). Base deficit was significantly found in 53.4% (P=0.004), while lactic acid was only elevated in 32.3% (P=0.005). Conclusion: ABG should be evaluated in all COVID-19 patients at admission. Children may present with atypical COVID symptoms as diarrhea, and children may resist changes in acid-base balance.

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“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic, resulting in a disease named coronavirus disease 2019 (COVID- 19), has spread worldwide since the beginning of 2020 (1,2). The World Health Organization (WHO) declared the COVID-19 outbreak to be a pandemic on March 11.…”

Section: Introductionmentioning

confidence: 99%

Pediatric Dilemma of the Third Wave Pandemic of COVID-19 in A Tertiary Care Hospital for Children

et al. 2023

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Background: In February 2020, a novel coronavirus caused a pandemic affecting children and adults with different presentations and outcomes. Objectives: The current study aimed to provide descriptive values regarding the clinical and laboratory profiles of children suspected of coronavirus disease 2019 (COVID-19). This purpose was achieved by studying all presentations, whether clinical or laboratory, typical or atypical, of suspected COVID-19-affected children at the peak of the third wave in a large tertiary hospital. Methods: This cross-sectional study enrolled 404 children with suspected COVID-19 who were tested in the Emergency Room of Abu El-Reesh Japanese Hospital, Cairo, Egypt, during the study period, which was from March 2021 to the end of October 2021. According to age, the patients were divided into four groups, including those under 2 years, the early childhood group (2 - 6 years), the late childhood group (6 - 12 years), and those over 12 years. The enrolled cases met the diagnostic criteria for COVID-19 according to the Egyptian Ministry of Health protocol. Results: In this study, 58 out of 404 tested children were positive for COVID-19 (14%), with a higher male predominance (n = 230/404, or 56.9% of the study group). The median age of the study participants was 1.6 years. Out of all presentations, the non-respiratory ones predominated and had the upper hand. It represented 62.9% (254/404) of the total presentations of the enrolled children. Among the non-respiratory manifestations, gastrointestinal ones were predominant (n = 63). Thrombocytopenia, leucopenia, and pancytopenia were significantly higher in children with non-respiratory manifestations than in those with respiratory manifestations. Conclusions: Children might have atypical manifestations of COVID-19 infections. The non-respiratory system could predominate in children. Thrombocytopenia could be a laboratory marker for COVID-19 infection, especially in those with predominant non-respiratory manifestations. Respiratory manifestations in children could be a guide for other systemic affections.

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Nutritional fat modulation as a non-pharmacological approach to children infected with COVID-19, a challenge in food biochemistry.

Cited by 4 publications

References 32 publications

Biochemical and Anthropometric Nutritional Assessment in Children Infected with COVID-19: A Cross-sectional Study

Biochemical and Anthropometric Nutritional Assessment in Children Infected with COVID-19: A Cross-sectional Study

Acid-Base Disturbances in Pediatrics Infected With COVID-19, A Cross Sectional Study

Pediatric Dilemma of the Third Wave Pandemic of COVID-19 in A Tertiary Care Hospital for Children

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