Nutritional Intervention- The Impact on Vitamins and Minerals Intake to Overweight and Obese Patients

Posea, Mihaela

doi:10.11648/j.jfns.20150303.13

Cited by 2 publications

(2 citation statements)

References 8 publications

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“…Other studies showed that the periodontal disease could be accelerated by destructive oxidative factors and final factors of advanced glicolisis [16]. The process is paralled by periodontitis itself as a source of oxidative stress able to modify the level of circulant adipocytokines such as leptin, which is known to accelerate the onset of resistance to insulin and metabolic syndrome [17][18][19][20].…”

Section: Resultsmentioning

confidence: 99%

Is There a Relationship Between Obesity and Periodontal Diseases?

Ormenişan¹,

Balmos²,

Golu³

et al. 2018

Rev. Chim.

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Obesity, a common metabolic disorder, is a condition for the development of chronic diseases, such as hypertension, diabetes mellitus, cardiovascular and cerebrovascular diseases. The present study evaluates the prevalence of periodontal diseases in Romania and their association with obesity, as a risk factor. This cross-sectional study included 170 subjects aged between 18-65, with healthy periodontal status, gingivitis, aggressive periodontitis and chronic periodontitis. All subjects completed the questionnaire with independent variables: age, education, socio-economic status, oral hygiene habits, smoking habit, the presence of any systemic diseases. Periodontal examination included: plaque index, gingival index, probing depth, clinical attachment level. Body mass index (BMI) and waist circumference (WC) were measured. Statistically significant correlations were found between periodontal diseases and BMI and WC: according to BMI 30.5% were obese, and 42.5% had high WC. 51.9% of obese participants had chronic periodontitis. Gingivitis and initial periodontitis do not influence BMI and WC, only the chronic periodontitis remained significantly associated with obesity. Our study suggests that there is an association between chronic periodontitis and BMI- defined obesity or WC, but further prospective studies should be carried on to establish the extent of it. The prevention and management of obesity may represent an approach to control periodontal health. Our study evaluates the prevalence of periodontal diseases in Romania and their association with obesity, as a risk factor.

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Section: Resultsmentioning

confidence: 99%

Is There a Relationship Between Obesity and Periodontal Diseases?

Ormenişan¹,

Balmos²,

Golu³

et al. 2018

Rev. Chim.

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“…Also, it induces insulin resistance and hepatic steatosis over time, diseases directly associated with obesity. [7,10] To remove the excess ECM and allow adipocyte hypertrophy, MMPs play a central part in the control of adipogenesis through the proteolytic activities that takes place during fat mass enlargement.…”

Section: Resultsmentioning

confidence: 99%

The Important Roles of Matrix Metalloproteinases in the Pathophysiology of Obesity

Mirică¹,

Ionescu²,

Mirică³

et al. 2017

Rev. Chim.

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Obesity involves the growth of adipose tissue cells (adipocytes and preadipocytes), as well as microvascular endothelial cells. Matrix metalloproteinases (MMPs) are relevant ezymes for the modulation of extracellular matrix (ECM) and adipocyte and preadipocytes differentiation. They are elevated in obese patients, generating abnormal ECM metabolism.[1]. This article proposes a thorough study of literature with focus on the important roles of matrix metalloproteinases in the pathophysiology of obesity. The article represents a narrative review based on an English-language PubMed research of the medical literature regardind important aspects of the proposed aim. MMP-2 activity was signi�cantly higher than MMP-9, both activities were detectable. MMP-9 was strongly correlated with body weight parameters before surgery, as well as after significant body weight reduction as a result of bariatric surgery. Concerning MMP-2 and MMP-9 they are also involved in the turnover of basement membranes both those of adipose tissue and endothelial. MMP-9 levels were moderately correlated with HDL cholesterol levels. Taken together, the present data suggest that changes in ECM through MMP-mediated degradation might play a critical role in the adipocyte differentiation process. These findings are detected both in clinical trials and in laboratory animal experiments. It is then tempting to speculate that the adipocyte-derived MMPs might represent a new pharmacological target for the inhibition of adipose tissue growth by inhibiting adipose differentiation as well as angiogenic process.

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Nutritional Intervention- The Impact on Vitamins and Minerals Intake to Overweight and Obese Patients

Cited by 2 publications

References 8 publications

Is There a Relationship Between Obesity and Periodontal Diseases?

Is There a Relationship Between Obesity and Periodontal Diseases?

The Important Roles of Matrix Metalloproteinases in the Pathophysiology of Obesity

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