Nutritional Interventions In The Treatment Of Acne Vulgaris: A Systematic Review Of Clinical Trials / Intervenções Nutricionais No Tratamento Da Acne Vulgaris: Uma Revisão Sistemática Dos Ensaios Clínicos

Abstract

The aim of this study is to review the literature about dietary interventions on acne vulgaris in order to support the development of more effective treatments in clinical practice. A systematic review of the literature, from clinical trials over the last five years, available in Pub Med and SciELO. The selected articles were analyzed according to the Jadad scale, CONSORT and risk of bias using the Cochrane protocol. CONSORT indicated that most of the evidence score was attributed in the titles, abstracts and some of the methods. In particular, the methods of the studies evaluated, when lacking detail, received lower scores, among the evidence, expressed as a percentage. The results, after using the Jadad scale, indicated a similar profile to that obtained with the CONSORT protocol. However, this tool is limited with regard to randomization and blinding. Using the Cochrane method, the risk of bias was evaluated. Results corroborated the evaluations by CONSORT and Jadad scale. Supplementation with n-3 fatty acids, Camellia sinensis, Berberis vulgaris, chromium, selenium and probiotics were significant, but results were limited for the treatment of acne vulgaris. Consumption of foods with increased glycemic load and chocolate indicated a correlation with an increase in acneiform lesions. Changes in nutritional status of alfa-tocopherol, cobalamin and folic acid were associated with the use of isotretinoin. There is a need to increase the quantity and quality of scientific evidence on the nutritional treatment of acne vulgaris in order to more effectively and safely guide the nutritional actions of clinical practice today.

Relação da disbiose e acne vulgaris: Tratamento com nutracêuticos e influências sobre a dieta em jovens adultos

“…Hodiernamente, sabe-se que é uma doença altamente prevalente entre os jovens adultos, afetando cerca de 64% deles (Cardoso, et al, 2021). Ambos os sexos são afetados, sendo sua maior incidência no público do sexo masculino (70%) do que no feminino (60%) devido fatores androgênicos (maior quantidade de testosterona em homens do que mulheres, que possuem mais progesterona e estrogênio) (Mota, 2021).…”

“…Aproximadamente 9,4% da população global tem acne vulgaris, classificando-a como a oitava doença mais prevalente em nível mundial. (Cardoso, et al, 2021). No Brasil, estima-se que a acne atinge cerca de 11 milhões de pessoas (Scipioni, et al, 2015).…”

“…No Brasil, estima-se que a acne atinge cerca de 11 milhões de pessoas (Scipioni, et al, 2015). Os principais fatores etiológicos da acne são: hereditários (genética), fases da vida (alterações hormonais), condição física (aumento de massa gorda, resistência à insulina, disbiose intestinal) e a composição da dieta (consumo de processados, falta de nutrientes, entre outros) (Cardoso et al, 2021).…”