Nutritional Management of Skin Diseases

Outerbridge, Catherine A.

doi:10.1002/9781118785669.ch11

Cited by 3 publications

(5 citation statements)

References 55 publications

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“…Immunologically speaking, proteins make up the vast majority of food antigens; therefore, great emphasis should be placed on proteincontaining dietary ingredients when targeting reduced diet antigenicity. In this regard, the administration of a novel antigen food represents a sound nutritional strategy to avoid the elicitation of acquired immunological hypersensitivity responses [114]. Notwithstanding, sensitisation to the new diet could easily occur in immune-dysregulated patients when intact proteins are fed [115].…”

Section: Main Nonpharmacological Therapies For Ciementioning

confidence: 99%

Nonpharmacological Treatment Strategies for the Management of Canine Chronic Inflammatory Enteropathy—A Narrative Review

Isidori

Corbee

Trabalza‐Marinucci

2022

Veterinary Sciences

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Chronic inflammatory enteropathy (CIE) refers to a heterogeneous group of idiopathic diseases of the dog characterised by persistent gastrointestinal (GI) clinical signs. If conventional dietary treatment alone would be unsuccessful, management of CIE is traditionally attained by the use of pharmaceuticals, such as antibiotics and immunosuppressive drugs. While being rather effective, however, these drugs are endowed with side effects, which may impact negatively on the animal’s quality of life. Therefore, novel, safe and effective therapies for CIE are highly sought after. As gut microbiota imbalances are often associated with GI disorders, a compelling rationale exists for the use of nonpharmacological methods of microbial manipulation in CIE, such as faecal microbiota transplantation and administration of pre-, pro-, syn- and postbiotics. In addition to providing direct health benefits to the host via a gentle modulation of the intestinal microbiota composition and function, these treatments may also possess immunomodulatory and epithelial barrier-enhancing actions. Likewise, intestinal barrier integrity, along with mucosal inflammation, are deemed to be two chief therapeutic targets of mesenchymal stem cells and selected vegetable-derived bioactive compounds. Although pioneering studies have revealed encouraging findings regarding the use of novel treatment agents in CIE, a larger body of research is needed to address fully their mode of action, efficacy and safety.

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Section: Main Nonpharmacological Therapies For Ciementioning

confidence: 99%

Nonpharmacological Treatment Strategies for the Management of Canine Chronic Inflammatory Enteropathy—A Narrative Review

Isidori

Corbee

Trabalza‐Marinucci

2022

Veterinary Sciences

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“…Algemeen wordt aangenomen dat 10% tot 20% van de dermatosen bij de hond te wijten is aan een voedselallergie (Friedeck, 2011). Daarnaast wordt gezien dat 75% van de honden met de dermatologische vorm van voedselallergie nog andere allergieën bezit (Outerbridge, 2012). Prevalentiecijfers zijn bij de hond helaas niet beschikbaar, in tegenstelling tot bij de mens, waar 5% van de volwassenen en 8% van de kinderen voedselallergie vertonen (Gupta et al, 2011;Sicherer en Sampson, 2014).…”

Section: Prevalentie En Voorkomenunclassified

“…In dat geval verdwijnen de symptomen tijdens het eliminatiedieet slechts partieel. Daarom is het heel belangrijk om de provocatiefase goed uit te voeren en te oordelen of er achteruitgang van de klinische toestand plaatsvindt of niet (Outerbridge, 2012). Alhoewel de provocatiefase bij de hond een zeer belangrijke stap is tijdens het testdieet, wordt dit in de praktijk vaak niet uitgevoerd.…”

Section: Provocatieunclassified

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Voedselallergie: een kwelling voor mens en dier

Janssens¹,

Dupont²,

Hesta³

2016

Vlaams Diergeneeskundig Tijdschrift

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Voedselallergie is een veel voorkomend probleem, zowel bij huisdieren als bij de mens. Zo wordt in de diergeneeskunde vaak voedselallergie vastgesteld bij de hond. Verschillende allergenen, zoals vlees, eieren en melk, worden aangeduid als boosdoener bij de hond en soms wordt er kruisreactiviteit gezien tussen verschillende allergenen. Bij de mens zijn vooral pinda’s, noten en koemelk bekend als veelvoorkomende antigenen. De symptomen variëren zowel bij de hond als bij de mens van huidklachten tot gastro-intestinale symptomen. De diagnosestelling van voedselallergie bij de hond gebeurt het beste door middel van een testdieet, bestaande uit twee fasen: de eliminatie- en provocatiefase. Andere testen, zoals de intradermale huidtest, serologie, de basofieldegranulatietest en gastroscopische voedselovergevoeligheidstest zijn ook beschikbaar. Echter, deze testen geven vaak weinig betrouwbare resultaten. De behandeling van voedselallergie berust in de eerste plaats op de eliminatie van het allergeen in de voeding. Dit kan eventueel worden aangevuld met medicatie, zoals corticosteroïden en antihistaminica.

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“…Skin diseases are one of the most frequent presenting complaints for cats and dogs in veterinary practice [ 1 , 2 , 3 ] and they are frequently caused by adverse food reactions, or AFR, which is the third most common skin allergy in dogs and the second most common skin allergy in cats [ 4 ]. The signs of moderate to severe cutaneous AFR (CAFR) are likely to substantially affect the overall quality of life of the pet.…”

Section: Introductionmentioning

confidence: 99%

DNA and Protein Analyses to Confirm the Absence of Cross-Contamination and Support the Clinical Reliability of Extensively Hydrolysed Diets for Adverse Food Reaction-Pets

Lesponne

Naar

Planchon

et al. 2018

Veterinary Sciences

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Adverse food reactions (AFR) are a common cause of skin diseases in cats and dogs. The correct diagnosis and management of AFR relies upon clinical nutrition. The reliability of commercial hypoallergenic diets commonly used in AFR has been questioned because studies have shown the presence of proteins not declared on the label ingredients. It is proposed that extensively hydrolysed protein-based diets constitute a reliable nutritional solution. Royal Canin Anallergenic™ Canine and Feline diets are formulated with very low molecular weight feather protein and purified corn starch. Protein gel electrophoresis and thin layer paper chromatography were used to characterize protein hydrolysis in these diets and their hydrolysed raw materials; protein species were identified by mass spectrometry. To detect cross-contaminating protein, species-specific DNA was measured and correlated with ancillary protein content using calibration curves. The only protein components detected in the extensively hydrolysed feather protein raw material were amino acids and small oligopeptides. GBSS-I (Granule-bound starch synthase 1) was detected in the finished diets; this has not been reported as a clinically apparent allergen in dogs or cats. The DNA threshold corresponding to the maximum acceptable level of ancillary protein was not exceeded in 99.9% of more than 2150 product batches tested and no products were released to the market with cross-contaminating proteins. These results demonstrate the extensive level of protein hydrolysis in Royal Canin Anallergenic™ Canine and Feline diets and the absence of cross-contaminating protein, both key requirements for a diet to be used during diagnosis and for management of pets with AFR.

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Nutritional Management of Skin Diseases

Cited by 3 publications

References 55 publications

Nonpharmacological Treatment Strategies for the Management of Canine Chronic Inflammatory Enteropathy—A Narrative Review

Nonpharmacological Treatment Strategies for the Management of Canine Chronic Inflammatory Enteropathy—A Narrative Review

Voedselallergie: een kwelling voor mens en dier

DNA and Protein Analyses to Confirm the Absence of Cross-Contamination and Support the Clinical Reliability of Extensively Hydrolysed Diets for Adverse Food Reaction-Pets

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