Nutritional predictors associated with malnutrition in continuous ambulatory peritoneal dialysis patients

Hiruy, Aschalew Fikru; Opoku, Sampson; Xiong, Qinmei; Jin, Qiman; Zhao, Jing; Lin, Xuechun; He, Siyu; Zuo, Xuezhi; Ying, Chenjiang

doi:10.1016/j.clnesp.2021.06.033

Cited by 7 publications

(2 citation statements)

References 47 publications

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“…Malnutrition is a very common complication in patients with KFRT due to metabolic and hormonal irregu-larities, systemic inflammation, inadequate nutrient intake, and adverse effects of kidney replacement therapy [23]. The prevalence of malnutrition among patients treated with dialysis is reported to be between 52.9% and 61.2% [24,25]. However, improvement in clinical and nutritional status has been demonstrated in kidney transplant patients [26].…”

Section: Discussionmentioning

confidence: 99%

Association of Serum Adropin Levels with Nutritional Status and Lipid Profile in Patients with Kidney Failure with Replacement Therapy

Yurtdaş Depboylu,

Acar Tek,

Deniz Güneş

et al. 2023

Galician med. j.

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Objective. This study aimed to determine serum adropin levels and to examine the relationship of serum adropin levels with nutritional status and lipid profile in patients with kidney failure with replacement therapy (KFRT). Methods. The study consisted of 88 subjects, including 30 patients treated with hemodialysis (HD), 29 patients treated with peritoneal dialysis (PD), and 29 patients who had undergone kidney transplantation (TX). The study included assessing anthropometric measurements, handgrip strength, bioelectrical impedance analysis, malnutrition-inflammation score, dietary intake, resting energy expenditure, and biochemical parameters. The patients’ food consumption was recorded for three days. The malnutrition-inflammation score (MIS) was calculated to assess the patients’ nutritional status. Blood samples were collected for serum adropin and other biochemical parameters. Results. Adropin levels were significantly higher in the TX group when compared to the HD group. Patients with low adropin levels had higher MIS, serum ferritin, and lower low-density lipoprotein-cholesterol (LDL-C) and total cholesterol (total-C) levels. Serum adropin levels were negatively correlated with the MIS and positively correlated with total-C, LDL-C, and HDL-C levels. Multiple linear regression analyses showed that the MIS (β=-0.25 p=0.038) and LDL-C level (β=0.29, p=0.007) were associated with serum adropin. Conclusions. Adropin may be considered as a new marker of nutritional status and possibly plays a role in the pathophysiological mechanisms and complications of patients with KFRT.

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Section: Discussionmentioning

confidence: 99%

Association of Serum Adropin Levels with Nutritional Status and Lipid Profile in Patients with Kidney Failure with Replacement Therapy

Yurtdaş Depboylu,

Acar Tek,

Deniz Güneş

et al. 2023

Galician med. j.

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“…Moreover, this recommendation for DPI is greater than the actual protein intake of the majority of PD patients as indicated by almost all dietary protein surveys [ 6 , 9 , 10 ]. Many published studies also suggested that patients with PD could maintain good nutritional status with a protein intake of 0.8 g/kg/d [ 11–16 ].…”

Section: Introductionmentioning

confidence: 99%

Longitudinal association between dietary protein intake and survival in peritoneal dialysis patients

Wang

Tang

et al. 2023

Renal Failure

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Background Decreased dietary protein intake (DPI) may lead to protein-energy malnutrition and may be associated with increased mortality risk. We hypothesized that longitudinal changes in dietary protein intake have independent associations with survival in peritoneal dialysis (PD) patients. Methods 668 stable PD patients were selected in the study from January 2006 to January 2018 and were followed up until December 2019. Their three-day dietary records were collected at the baseline (the sixth month after PD) and thereafter every 3 months for two and a half years. The latent class mixed models (LCMM) were used to identify subgroups of PD patients with similar longitudinal trajectories of DPI. The relation between DPI (baseline and longitudinal data) and survival was examined using Cox model to estimate death hazard ratios. Meanwhile, different formulae were used to assess nitrogen balance. Results The results showed that baseline DPI ≤ 0.60g/kg/day was associated with the worst outcome in PD patients. Patients with DPI 0.80–0.99g/kg/day and DPI ≥ 1.0g/kg/day both presented positive nitrogen balance; patients with DPI 0.61–0.79g/kg/day presented obviously negative nitrogen balance. Longitudinal association between time-dependent DPI and survival was found in PD patients. The consistently low DPI' (0.61–0.79g/kg/d) group was correlated with increased death risk as compared with the 'consistently median DPI' group (0.80–0.99g/kg/d, HR = 1.59, p = 0.008), whereas there was no difference in survival between 'consistently median DPI' group and 'high-level DPI' group (≥1.0 g/kg/d, p > 0.05). Conclusion Our study revealed that DPI ≥ 0.8 g/kg/day was beneficial to the long-term outcome for the PD population.

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Effect of multidisciplinary medical nutrition therapy on the nutrition status of patients receiving peritoneal dialysis: A randomized controlled trial

Liang,

Xu,

Guo

et al. 2024

Nut in Clin Prac

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BackgroundMalnutrition is a prevalent complication in patients undergoing peritoneal dialysis (PD). This study established a multidisciplinary team for medical nutrition therapy (MNT) to investigate the impact of this approach on enhancing the nutrition, anemic, and microinflammatory status of patients receiving PD.MethodsThis randomized controlled trial study involved 81 patients undergoing PD (n = 41 in the intervention group, n = 40 in the control group). The intervention group received comprehensive MNT management, whereas the control group received standard nutrition care. The intervention spanned a 6‐month period. Various nutrition parameters, markers of anemia, and microinflammatory indexes were assessed before the intervention, at 3 months, and at 6 months postintervention. Repeated‐measures analysis of variance and the nonparametric Scheirer‐Ray‐Hare test were used for within‐group and between‐group comparisons.ResultsThere were no statistically significant differences between the groups in terms of age, sex, duration of dialysis, primary disease, or baseline prenutrition inflammation data. At 6 months postintervention, the intervention group exhibited higher levels of serum albumin, blood calcium, serum iron, hemoglobin, total iron‐binding capacity, body mass index, midarm circumference, triceps skinfold thickness, handgrip strength, and daily energy and protein intake compared with the control group (P < 0.05). Additionally, the intervention group demonstrated lower levels of subjective nutrition assessment value, C‐reactive protein, and neutrophil‐to‐lymphocyte ratio than the control group (P < 0.05), with no statistically significant differences in other markers after interventions.ConclusionMultidisciplinary MNT can ameliorate the nutrition status of patients receiving PD, decrease the incidence of malnutrition, and improve anemia and microinflammatory outcomes.

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Nutritional predictors associated with malnutrition in continuous ambulatory peritoneal dialysis patients

Cited by 7 publications

References 47 publications

Association of Serum Adropin Levels with Nutritional Status and Lipid Profile in Patients with Kidney Failure with Replacement Therapy

Association of Serum Adropin Levels with Nutritional Status and Lipid Profile in Patients with Kidney Failure with Replacement Therapy

Longitudinal association between dietary protein intake and survival in peritoneal dialysis patients

Effect of multidisciplinary medical nutrition therapy on the nutrition status of patients receiving peritoneal dialysis: A randomized controlled trial

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