Nutritional Profile, Antioxidative and Antihyperglycemic Properties of Padina tetrastromatica from Tioman Island, Malaysia

Abstract

Seaweeds are an important ingredient of functional foods recommended for daily food, due to their unique compositions and nutritional value. Padina tetrastromatica is a brown edible seaweed that is commonly found along the coastal regions of Peninsular Malaysia and consumed as food by some coastal communities. This study investigates the nutritional and antihyperglycaemic potential of P. tetrastromatica extracts, which is generally accepted as an important functional food. In our methodology, we induced diabetes intraperitoneally in experimental animals with a dose of 65 mg kg−1 body weight of streptozotocin. Oral treatment with 200 and 400 mg kg−1 of P. tetrastromatica ethanolic and ethyl acetate extracts were initiated, respectively, to experimental rats once daily for 18 days. Metformin was used as the positive control. Biochemical estimations and histopathological analysis were included in this study. Treatment with P. tetrastromatica extracts significantly lowered the plasma glucose levels in Streptozotocin-induced diabetic rats. In addition, P. tetrastromatica extract treatment also showed a significant reduction in serum alanine transaminase levels. However, no significant changes were observed in serum aspartate transaminase levels. The ethyl acetate extract of P. tetrastromatica at 400 mg kg−1 dose shows some nephroprotective effect, which is observed from the significant increase in the plasma albumin levels. Histopathological evaluation revealed no marked morphological changes in tissues of the isolated organs of the ethyl acetate extract-treated group, revealing the safe nature of P. tetrastromatica.

Nutritional composition and phenolic contents of Gracilariopsis longissima, Padina tetrastromatica and Ulva intestinalis from the Bay of Bengal, Bangladesh coast

“…The protein content of the three studied species ranged from 8.30 ± 0.37 % ( P. tetrastromatica ) to 30.63 ± 0.90 % ( G. longissima ) of DW and significantly higher (P < 0.05) amount of protein was found in G. longissima ( Table 1 ). The current findings were similar to the findings of Jannat-Alipour et al [ 26 ]; Rosemary et al [ 18 ]; Palaniveloo et al [ 11 ]. The content of protein in seaweeds are generally higher in red seaweeds than the brown and green seaweeds [ 8 , 27 ] which supports our current findings.…”

“…This is because the ratio of sodium (Na) to potassium (K) in this product is less than 1, which aligns with the recommended dietary choices for individuals with high blood pressure [ 32 ]. Additionally, seaweeds with low Na/K ratios are good for replacing sodium chloride [ 11 ]. According to seaweed species, location, wave, season, environment, physiological parameters, processing type, and mineralization technique, mineral concentrations might differ [ 33 ].…”

“…According to several research [ 4 , 8 ], macroalgae have an intriguing nutritional and chemical constitution and are becoming more popular as meals rich in protein for human and animal consumption. According to several studies, seaweeds have a large number of proteins, minerals, vitamins, phenolic substances, polyunsaturated fats, essential amino acids, and other important compounds while having low levels of saturated fat [ [9] , [10] , [11] ]. Two crucial aspects of nutrition are protein and its amino acid composition.…”

Nutritional values of Sargassum sp., Ulva sp., and Padina sp. from South East Molluca Island waters

“…D'Armas et al [24] reported that the carbohydrate content of Padina pavonica (43,39%), Sargassum (40.04%) and Ulva lactuca (45.32%) was higher than in this study. Whereas previous study reported that crude carbohydrate of Sargassum hystrix (31.53%) [21], Ulva (16.63%) [26] and Padina (23.16%) [27]. Differences in carbohydrate content are determined by water quality conditions [28].…”

In Vitro and In Vivo Anticancer and Genotoxicity Profiles of Green Synthesized and Chemically Synthesized Silver Nanoparticles

“…Hence, the present study demonstrated a comparative study between the chemically synthesized silver nanoparticles with green synthesized silver nanoparticles (using P. tetrastromatica) and estimated their possible role in controlling melanoma cancer both in in vitro and in vivo mice models. ,− To perform a risk assessment of these two types of silver nanoparticles, the genotoxicological profile was also determined. , The overall study demonstrates the first ever comparison of both therapeutic efficacies and genotoxicological profiles of these two silver nanoparticles (green and chemical synthesized) in both in vitro and in vivo models that are very much essential before their clinical use.…”