Nutritional risk assessment in critically ill cancer patients: systematic review

Fruchtenicht, Ana Valéria Gonçalves; Poziomyck, Aline Kirjner; Kabke, Geórgia Brum; Loss, Sérgio Henrique; Antoniazzi, Jorge Luiz; Steemburgo, Thais; Moreira, Luís Fernando

doi:10.5935/0103-507x.20150032

Cited by 37 publications

(36 citation statements)

References 23 publications

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“…Albumin is an acute phase reactant that can be decreased in infections (Wierdak et al 2018). The association of albumin with the nutritional status is controversial and apparently varies among patient populations (Fuhrman et al 2004;Kuzuya et al 2007;Baron et al 2010;Gama-Axelsson et al 2012;Fruchtenicht et al 2015;Academy of Nutrition and Dietetics 2016;Bharadwaj et al 2016;Marcason 2017). Other laboratory parameters were also disturbed in SCAP patients (such as platelets, liver function, and natriuretic peptide), but whether they are causes or consequences of SCAP is unknown.…”

Section: Discussionmentioning

confidence: 99%

Anemia and Low Albumin Levels Are Associated with Severe Community-Acquired Pneumonia in Pregnancy: A Case-Control Study

Mai

et al. 2019

Tohoku J. Exp. Med.

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Community-acquired pneumonia (CAP) is the most common form of pneumonia in pregnancy and may lead to severe adverse maternal and fetal outcomes. Severe CAP (SCAP) is defined as the need for invasive mechanical ventilation and with septic shock with the need for vasopressors. This study aimed to analyze the clinical characteristics and factors associated with SCAP in pregnancy. The present study was a case-control study of pregnant women hospitalized between September 2012 and September 2017 at nine tertiary hospitals in China. Among 358,424 pregnant women, we found 35 SCAP cases and 393 common CAP cases. The 35 SCAP cases were matched 1:4 with common CAP cases (n = 140), based on patient age and gestational weeks. Infection indicators, hemoglobin, platelets, coagulation function, liver, and kidney function markers, myocardial enzyme, arterial oxygen pressure/fraction inspired oxygen (PO 2 / FiO 2), and partial echocardiographic results were different between the two groups at admission (all P < 0.05). The univariable analyses indicated significant differences for hemoglobin, BMI, irregular obstetric examination, albumin, and white blood cells (all P < 0.05) between the common CAP and SCAP groups. The multivariable logistic regression analysis showed that hemoglobin (OR = 0.87, 95% CI: 0.77-0.97, P = 0.01), BMI (OR = 0.42, 95% CI: 0.22-0.81, P = 0.01), and serum albumin (OR = 0.37, 95% CI: 0.19-0.69, P = 0.002) were independently associated with SCAP. Anemia and low serum albumin are possibly associated with SCAP in pregnancy. The results indicate that anemia and albumin levels should be examined and properly treated in pregnant women with CAP.

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Section: Discussionmentioning

confidence: 99%

Anemia and Low Albumin Levels Are Associated with Severe Community-Acquired Pneumonia in Pregnancy: A Case-Control Study

Mai

et al. 2019

Tohoku J. Exp. Med.

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“…In the last 20 years, many screening instruments have been developed but most of these are too complicated for routine use in daily practices [13]. Until the present, no instruments have been devised that are sensitive and specific enough to become the golden standard for the assessment of nutrition [17]. Although there is no generally accepted method for assessing the nutritional status of patients, the assessment should establish the nutritional condition of a subject.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of malnutrition / malnutrition risk in cancer patients: experince of an oncology outpatient clinic in Turkey

Koç

Can²,

Alacacıoğlu

et al. 2018

Family Practice and Palliative Care

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Introduction: The objective of this study is to determine the prevalence of malnutrition risk (MR)/malnutrition (MN) in cancer patients using MNA. Methods: This observational study was conducted with cancer patients in the Izmir Katip Celebi University Ataturk Training and Research Hospital Medical Oncology Outpatient Clinic. Demographic data, daily functional status according to the Eastern Cooperative Oncology Group (ECOG), nutritional status according to Mini Nutrition Assessments (MNA) and anthropometric measurements obtained with TANITA Body Composition Analyzer Model TBF-300 (TANITA) were used in the evaluation of patients. Results: The study enrolled 296 oncology patients. The mean age was 58.34 ± 11.60 years. Two hundred and eight (70.3%) of the patients were women. The most common three tumor types were breast tumors (43.2%; n=128); gastrointestinal tract tumors (33.1%; n=98), genitourinary tract tumors (10.8%: n=32). The mean BMI of the patients was 27.45 ± 5.75 m2/kg. According to MNA 118 of the patients were in normal nutritional status (39.9%). 130 of them were at the risk of malnutrition (43.9%), 48 of them were malnourished (16.2%). Conclusion: In cancer patients, the prevalence of malnutrition and malnutrition risk is significantly high, and this may alter the patient's life quality and expectancy. Therefore, the nutritional status of every patient that is diagnosed with cancer should be assessed in early stages of the disease.

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“…However, each parameter of the CONUT score has been reported to be associated with outcome in patients with GI and HPB malignancies. It is well recognized that the serum albumin plays an important role to reflect metabolic status as well as systematic inflammatory response in cancer patients [4,29]. Moreover, a low albumin level is not only associated with poor prognosis in various kinds of malignancies [6,25] but also found to be an independent predictor of postoperative complications in many studies [30][31][32].…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, accurate nutritional evaluation of patients is very important. Although several nutritional assessment tools, such as Patient-Generated Subjective Global Assessment, nutritional risk index, malnutrition universal screening tool and the nutritional risk screening tool 2002 [2,3], have been developed, the precise evaluation including nutritional risk and outcome is still controversial in cancer patients [4].…”

Section: Introductionmentioning

confidence: 99%

The Controlling Nutritional Status Score and Postoperative Complication Risk in Gastrointestinal and Hepatopancreatobiliary Surgical Oncology: A Systematic Review and Meta-Analysis

Takagi¹,

Domagała²,

Polak

et al. 2019

Ann Nutr Metab

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The controlling nutritional status (CONUT) score is associated with prognosis in gastrointestinal (GI) cancer patients, but the clinical significance of the CONUT score for postoperative short-term outcome remains controversial. The aim of this study was to investigate the impact of the CONUT score on postoperative outcomes in patients with GI and hepatopancreatobiliary (HPB) cancers. We conducted a systematic literature search of Embase, Medline Ovid, Web of Science, Cochrane CENTRAL, and Google Scholar. Meta-analyses were performed to estimate the pooled risk ratio (RR) for postoperative complications in patients with lower CONUT score versus higher CONUT score. Furthermore, we explored the most appropriate cutoff value of the CONUT score to predict postoperative complications. Ten retrospective studies (5,138 patients) were included in this meta-analysis. Patients with higher CONUT score had an increased risk of mortality (RR 5.38, 95% CI 2.19–13.2, p < 0.001, I² = 0%), postoperative major complications (RR 1.56, 95% CI 1.05–2.33, p= 0.03, I² = 79%), and overall complications (RR 1.38, 95% CI 1.16–1.63, p < 0.001, I² = 6%). We found that the cutoff of CONUT ≤4 vs. CONUT ≥5 had the highest pooled RR compared with other cutoff values (RR 4.79, 95% CI 0.97–23.5, p= 0.05, I² = 91%). In conclusion, the present study suggests that the preoperative CONUT score was associated with an increased risk of mortality and complications in GI and HPB surgical oncology. Patients with higher CONUT score as compared with those having a lower score had approximately a fivefold mortality risk and an increased risk up to 55% on major and overall complications after GI and HPB surgery. Our analysis indicates that the appropriate cutoff value of the CONUT score to predict postoperative major complications would be between 4 and 5. The preoperative evaluation of the CONUT score would be helpful for predicting the risk of postoperative outcomes.

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Nutritional risk assessment in critically ill cancer patients: systematic review

Cited by 37 publications

References 23 publications

Anemia and Low Albumin Levels Are Associated with Severe Community-Acquired Pneumonia in Pregnancy: A Case-Control Study

Anemia and Low Albumin Levels Are Associated with Severe Community-Acquired Pneumonia in Pregnancy: A Case-Control Study

Prevalence of malnutrition / malnutrition risk in cancer patients: experince of an oncology outpatient clinic in Turkey

The Controlling Nutritional Status Score and Postoperative Complication Risk in Gastrointestinal and Hepatopancreatobiliary Surgical Oncology: A Systematic Review and Meta-Analysis

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