Nutritional status and cognitive performance of mother–child pairs in Sidama, Southern Ethiopia

Bogale, Alemtsehay; Stoecker, Barbara J.; Kennedy, Tay; Hubbs‐Tait, Laura; Thomas, David; Abebe, Yewelsew; Hambidge, K. Michael

doi:10.1111/j.1740-8709.2011.00345.x

Cited by 35 publications

(45 citation statements)

References 25 publications

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“…Studies on only preterm births or low/very low birth weight newborns ( k = 4; [30,31,32,33]) were excluded because these studies were likely to produce different results due to the effect of birth weight and gestational age on the outcome of interest. Additional exclusion criteria included: (1) use of non-standardized psychometric tests ( k = 1; [34]), (2) sole focus on gross motor milestones ( k = 1; [35]), (3) cross-sectional observational designs that compared iodine-sufficient with iodine-deficient communities as they did not control for obvious confounds and did not provide sufficient clusters for analysis ( k = 2; [36,37]), and (4) stratification of mothers based on an indicator of thyroid dysfunction, the thyroid peroxidase antibody (TPOAb), rather than of their iodine status ( k = 1; [38]).…”

Section: Methodsmentioning

confidence: 99%

Iodine and Mental Development of Children 5 Years Old and Under: A Systematic Review and Meta-Analysis

et al. 2013

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Several reviews and meta-analyses have examined the effects of iodine on mental development. None focused on young children, so they were incomplete in summarizing the effects on this important age group. The current systematic review therefore examined the relationship between iodine and mental development of children 5 years old and under. A systematic review of articles using Medline (1980–November 2011) was carried out. We organized studies according to four designs: (1) randomized controlled trial with iodine supplementation of mothers; (2) non-randomized trial with iodine supplementation of mothers and/or infants; (3) prospective cohort study stratified by pregnant women’s iodine status; (4) prospective cohort study stratified by newborn iodine status. Average effect sizes for these four designs were 0.68 (2 RCT studies), 0.46 (8 non-RCT studies), 0.52 (9 cohort stratified by mothers’ iodine status), and 0.54 (4 cohort stratified by infants’ iodine status). This translates into 6.9 to 10.2 IQ points lower in iodine deficient children compared with iodine replete children. Thus, regardless of study design, iodine deficiency had a substantial impact on mental development. Methodological concerns included weak study designs, the omission of important confounders, small sample sizes, the lack of cluster analyses, and the lack of separate analyses of verbal and non-verbal subtests. Quantifying more precisely the contribution of iodine deficiency to delayed mental development in young children requires more well-designed randomized controlled trials, including ones on the role of iodized salt.

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Section: Methodsmentioning

confidence: 99%

Iodine and Mental Development of Children 5 Years Old and Under: A Systematic Review and Meta-Analysis

et al. 2013

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“…In Africa, it has been used to study cognitive development and nutrition in Ethiopia (Bogale et al, 2013), Democratic Republic of Congo (Boivin et al, 2013; Bumoko et al, 2015) and South Africa (Taljaard et al, 2013; Rochat et al, 2016), among HIV infected children in Uganda (Boivin et al, 2010; Ruel et al, 2012; Brahmbhatt et al, 2017), and cerebral malaria in Senegal (Boivin, 2002), and Uganda (Bangirana et al, 2009). KABC-II has different sub-tests and is used in children aged 3–18 years.…”

Section: Methodsmentioning

confidence: 99%

Maternal alcohol consumption during pregnancy and child’s cognitive performance at 6–8 years of age in rural Burkina Faso: an observational study

Sanou

Diallo

Holding³

et al. 2017

PeerJ

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BackgroundIn Burkina Faso, it is not uncommon for mothers to drink alcohol, even during pregnancy. We aimed to study the association between maternal alcohol consumption during pregnancy and the child’s cognitive performance using the Kaufman Assessment Battery for Children, 2nd edition (KABC-II) and the Children’s Category Test Level 1 (CCT-1) in rural Burkina Faso.MethodsWe conducted a follow-up study of a community cluster-randomised Exclusive breastfeeding trial, and re-enrolled the children in rural Burkina Faso. A total of 518 children (268 boys and 250 girls) aged 6–8 years were assessed using the KABC-II and the CCT-1. We examined the effect size difference using Cohen’s d and conducted a linear regression analysis to examine the association.ResultsSelf-reported alcohol consumption during pregnancy was 18.5% (96/518). Children whose mothers reported alcohol consumption during pregnancy performed significantly poorly for memory and spatial abilities tests from small effect size difference for ‘Atlantis’ (0.27) and ‘Triangle’ (0.29) to moderate effect size difference for ‘Number recall’ (0.72) compared to children whose mothers did not consume alcohol during pregnancy; the exposed children scored significantly higher errors with a small effect size (0.37) at problem solving (CCT-1) test compared to unexposed children.At unstandardized and standardized multivariable analysis, children whose mothers reported alcohol consumption during pregnancy performed significantly poorer for memory-‘Atlantis’ (p = 0.03) and ‘Number recall’ (p = 0.0001), and spatial ability tests-‘Triangle’ (p = 0.03); they scored significantly higher errors at problem solving CCT-1 test (p = 0.002); all the results were adjusted for age, sex, schooling, stunting, father’s education, mother’s employment and the promotion of exclusive breastfeeding. No statistical association was found for visual abilities-‘Conceptual Thinking’, ‘Face recognition’, ‘Story completion’, and reasoning tests-‘Rover’, ‘Block counting’, and ‘Pattern Reasoning’.ConclusionMaternal alcohol consumption during pregnancy is associated with poorer cognitive performance for memory, spatial ability, and problem solving tests in the offspring in rural Burkina Faso. Futures studies needs to assess in more detail the maternal alcohol consumption patterns in Burkina Faso and possible preventive strategies.

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“…An increasing body of evidence indicates that poor nutritional status during early childhood has a negative impact on cognitive development (Lozoff 2000;Grantham-McGregor & Ani 2001;Liu et al 2003;Laus et al 2011;Galler et al 2012;Bogale et al 2013;Waber et al 2014) externalizing behavior (Liu et al 2004;Galler et al 2011;Liu & Raine 2011) even after controlling for social adversity. Nutritional supplementation, on the other hand, has been shown to reduce behavioral problems in early childhood (Berglund et al 2013) as well as in adolescence (Raine et al 2015).…”

Section: Introductionmentioning

confidence: 99%

Nutritional status and social behavior in preschool children: the mediating effects of neurocognitive functioning

Liu

Raine

2016

Maternal & Child Nutrition

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Early malnutritional status has been associated with reduced cognitive ability in childhood. However, there are almost no studies on the effect of malnutrition on positive social behavior, and no tests of possible mediating mechanisms. This study tests the hypothesis that poor nutritional status is associated with impaired social functioning in childhood, and that neurocognitive ability mediates this relationship. We assessed 1553 male and female 3-year-olds from a birth cohort on measures of malnutrition, social behavior and verbal and spatial neurocognitive functions. Children with indicators of malnutrition showed impaired social behavior (p <.0001) as compared with children in the control group with adequate nutritional status. These associations even persisted after controlling for social adversity and parental education. Findings were not moderated by gender or ethnicity, and there was no interaction effect with parental education. A dose–response relationship was observed between degree of malnutrition and degree of social behavior, with increased malnutrition associated with more impaired social behavior. Neurocognitive ability was found to mediate the nutrition–social behavior relationship. The mediation effect of neurocognitive functioning suggests that poor nutrition negatively impacts brain areas that play important roles in developing positive social behavior. Findings suggest that reducing poor nutrition, alternatively promoting good nutrition, may help promote positive social behavior in early childhood during a critical period for social and neurocognitive development, with implications for improving positive health in adulthood.

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Nutritional status and cognitive performance of mother–child pairs in Sidama, Southern Ethiopia

Cited by 35 publications

References 25 publications

Iodine and Mental Development of Children 5 Years Old and Under: A Systematic Review and Meta-Analysis

Iodine and Mental Development of Children 5 Years Old and Under: A Systematic Review and Meta-Analysis

Maternal alcohol consumption during pregnancy and child’s cognitive performance at 6–8 years of age in rural Burkina Faso: an observational study

Nutritional status and social behavior in preschool children: the mediating effects of neurocognitive functioning

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