Nutritional Status and Respiratory Mechanics

Braun, Norma M. T.

doi:10.1007/978-1-4471-3840-2_7

Cited by 1 publication

(1 citation statement)

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“…This may be a consequence of differences in alveolar growth, since in animals, at least, factors such as protein malnutrition have been associated with alterations in the postnatal formation of alveoli (Brody and Vaccaro, 1979). In humans, nutritional deprivation decreases ventilatory responses, reduces respiratory muscle function, and disturbs lung development (Braun, 1992).…”

Section: Lung Functionmentioning

confidence: 99%

Growth of Han migrants at high altitude in central Asia

Weitz

Garruto

2004

American J Hum Biol

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Han Chinese of low-altitude descent have been living in Qinghai Province of Western China for at least two millennia. For most of this time they have lived at elevations under 2,500 m. However, during the last four decades an increasing number of Han have moved into high-altitude towns at elevations over 3,000 m, and some above 4,000 m. There are now sufficient numbers of Han descendants who have been born and raised at high altitude to allow a comparison of their morphological and physiological growth patterns with low-altitude Han to detect the effect of hypoxia. The field study reported here was conducted by collaborating Chinese and American researchers over a 6-year period, and included 1,227 Han living at high altitude in Qinghai and at low altitude near Beijing. This study demonstrates that Han born and raised at high altitude are smaller and lighter than those at low altitude-particularly as children and adolescents. Slower growth at high altitude may be a consequence of hypoxia, but it also corresponds to poorer economic conditions in rural Qinghai Province, and thus may reflect nutritional inadequacies. Differences in altitude and/or nutrition do not seem to affect thorax dimensions, since, relative to stature, chest dimensions are similar at both high and low altitudes. Nevertheless, lung volumes are higher among Han at high altitude, possibly reflecting the influence of hypoxia on alveolar growth. The hematological values of Han growing up at 3,200 m are not different from those at low altitude-an unusual finding relative to other low-altitude groups that may reflect population differences in response to hypoxia. At 3,800 m and 4,300 m, however, Han show elevated hemoglobin relative to Han at low altitude.

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Section: Lung Functionmentioning

confidence: 99%