Nutritional Status of Free-Living Alzheimer’s Patients

Renvall, Marian; Spindler, Audrey A.; Ramsdell, Joe; Paskvan, Monica

doi:10.1097/00000441-198907000-00004

Cited by 79 publications

(31 citation statements)

References 23 publications

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“…In our study of nursing home patients, we included psycho-geriatric nursing home patients as a population of convenience, since this population is more stable than somatic patients (less co-morbidity and less use of medication (Larsson et al, 1990)). Furthermore, it has been shown that this population often experiences weight loss and has an increased risk for an inadequate nutritional status (Renvall et al, 1989;Moreiras et al, 1991;Cronin-Stubbs et al, 1997).…”

Section: Introductionmentioning

confidence: 99%

Study of the effect of a liquid nutrition supplement on the nutritional status of psycho-geriatric nursing home patients

Wouters-Wesseling¹,

Wouters²,

Kleijer

et al. 2002

Eur J Clin Nutr

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Objectives: To evaluate the acceptance of a multinutrient liquid nutrition supplement in psycho-geriatric nursing home patients and the effect on weight, plasma nutrients and activities of daily life. Design: Double-blind, placebo-controlled 12-week intervention study. Setting: Two nursing homes in Boxtel, The Netherlands. Subjects: Forty-two (body mass index (BMI) < 23 kg=m 2 for men or < 25 kg=m 2 for women) psycho-geriatric nursing home patients aged 60 y or over. Interventions: Provision with a complete micronutrient-enriched liquid nutrition supplement of 125 ml and 0.6 MJ (135 kcal) or placebo twice daily during daytime between main meals. Study parameters were assessed at 0, 6 and 12 weeks. Main Outcome for Measures: Weight, Barthel index of daily activities, several plasma values (albumin, C-reactive protein (CRP), homocysteine, thiamine, thiamine diphosphate (TDF), vitamin B 6 , vitamin B 12 , folic acid, vitamin D), bowel function. Results: The supplement was well accepted. Thirty-five patients completed the intervention period (16 control group; 19 supplement group). Baseline daily nutrient intake was low. A statistically significant improvement was observed for body weight (difference between groups 2.2 kg, P ¼ 0.03), and homocysteine, vitamin B 1 , TDF, vitamin B 6 , vitamin B 12 , folate and vitamin D in the supplement group compared to the placebo group. No significant difference was observed in the Barthel index (mean difference 7 0.3 AE 1.1 for both groups). No difference in occurrence of diarrhoea was observed. Conclusions: The study shows that nutritional supplementation is well accepted and can improve the nutritional status of psycho-geriatric nursing home patients.

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Section: Introductionmentioning

confidence: 99%

Study of the effect of a liquid nutrition supplement on the nutritional status of psycho-geriatric nursing home patients

Wouters-Wesseling¹,

Wouters²,

Kleijer

et al. 2002

Eur J Clin Nutr

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“…No statistically significant association was found between the dietary intake levels of folate and cognitive function scores, except that, as before, Goodwin et al [5] found that participants with folate intake levels in the bottom 5% had significantly worse Wechsler verbal memory test scores than those with levels in the top 90%. Renvall et al [7] found that participants with Alzheimer's disease had dietary intake levels of folate similar to those of normal participants.…”

Section: Folate Intakementioning

confidence: 97%

“…This section summarizes the findings from three (retrospective and prospective) longitudinal studies [2,3] and five cross-sectional studies [4][5][6][7][8] that examined the association between the dietary intake levels of B vitamins and cognitive function or the risk of age-related neurodegenerative diseases. The report included all populations for longitudinal studies, whereas only noninstitutionalized or free-living populations were included for cross-sectional studies in order to assess their "usual" dietary intake levels.…”

Section: Association Of Dietary Intake Levels Of B Vitamins With Age-mentioning

confidence: 99%

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Effects of Folate and Vitamin B₁₂ on Cognitive Function in Adults and the Elderly

Rosenberg¹

2008

Food Nutr Bull

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“…To date, findings have been relatively inconsistent. Some have reported intakes adequate to meet requirements (Winograd et al, 1991;Spindler et al, 1996), higher (Deijen et al, 2003) or similar to those without cognitive impairment (Renvall et al, 1989;Franzoni et al, 1996), whereas others have reported intake insufficient to meet requirements and lower than those without cognitive impairment (Litchford and Wakefield, 1987).…”

Section: Introductionmentioning

confidence: 99%

Lower limb fracture, cognitive impairment and risk of subsequent malnutrition: a prospective evaluation of dietary energy and protein intake on an orthopaedic ward

Miller¹,

Bannerman

Daniels

et al. 2006

Eur J Clin Nutr

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Objective: To report the dietary energy and protein intake of undernourished older adults (with and without cognitive impairment) admitted to hospital following a lower limb fracture and to determine whether dietary intakes met estimated requirements. Design: An observational study of a sequential sample. Setting: The orthopaedic ward of a South Australian metropolitan teaching hospital. Subjects: Sixty-eight patients aged X70 years screened as undernourished and admitted to hospital following lower limb fracture (50% cognitively impaired) provided 3 to 5 days of dietary data. Major outcome methods: Dietary energy and protein intake. Methods: Dietary assessment using plate waste methodology and snack record charts commenced within 6 days postinjury and continued for up to five consecutive days or until discharge. Estimated resting energy requirements were calculated and adjusted for activity equivalent to bed rest and physiological stress. Protein requirements were calculated as 1 g/kg/day. Cognition was assessed using the Short Portable Mental Status Questionnaire. Results: Cognitively impaired participants and those without cognitive impairment consumed, mean (95% CI) respectively, 3661 kJ/day (3201, 4121) versus 4208 kJ/day (3798, 4619) and 38 g (33, 44) versus 47 g (41, 52) protein/day. Cognitively impaired participants consumed mean (95% CI) 48% (43, 53) of estimated total energy expenditure and 78% (69, 87) of estimated protein requirements. Conclusions: Orthopaedic fracture patients at greatest nutritional risk, including those with cognitive impairment, do not achieve estimated energy or protein requirements from diet alone. Effective methods of achieving requirements in this vulnerable group are needed before improvements in outcomes will be observed.

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Nutritional Status of Free-Living Alzheimer’s Patients

Cited by 79 publications

References 23 publications

Study of the effect of a liquid nutrition supplement on the nutritional status of psycho-geriatric nursing home patients

Study of the effect of a liquid nutrition supplement on the nutritional status of psycho-geriatric nursing home patients

Effects of Folate and Vitamin B₁₂ on Cognitive Function in Adults and the Elderly

Lower limb fracture, cognitive impairment and risk of subsequent malnutrition: a prospective evaluation of dietary energy and protein intake on an orthopaedic ward

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Nutritional Status of Free-Living Alzheimer’s Patients

Cited by 79 publications

References 23 publications

Study of the effect of a liquid nutrition supplement on the nutritional status of psycho-geriatric nursing home patients

Study of the effect of a liquid nutrition supplement on the nutritional status of psycho-geriatric nursing home patients

Effects of Folate and Vitamin B12 on Cognitive Function in Adults and the Elderly

Lower limb fracture, cognitive impairment and risk of subsequent malnutrition: a prospective evaluation of dietary energy and protein intake on an orthopaedic ward

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Effects of Folate and Vitamin B₁₂ on Cognitive Function in Adults and the Elderly