Nutritional Status Parameters as Risk Factors for Mortality in Cancer Patients

Maurício, Sílvia Fernandes; Ribeiro, Hélio; Correia, María Isabel Toulson Davisson

doi:10.1080/01635581.2016.1188971

Cited by 22 publications

(16 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The association between undernutrition and morbidity and mortality is known and widely documented in the adult population 7,25,26,34,[41][42][43][44][45] ; however, there is a lack of literature that demonstrates this association, evaluated particularly by body composition indicators, in sick and critically ill children. Thus, despite having several limitations, our study reinforces the importance of nutrition assessments in critically ill children and suggests that body composition may be useful not only for nutrition diagnosis and monitoring, but also for an additional indicator in estimating death risk and PICU LOS in this population.…”

Section: Discussionmentioning

confidence: 99%

Bioelectrical Impedance Phase Angle and Morbidity and Mortality in Critically Ill Children

et al. 2018

View full text Add to dashboard Cite

Background Nutrition markers may be useful for diagnosis and monitoring and, also, as additional indicators of estimating death risk. We tested the association of body composition indicators (mid–upper arm circumference and phase angle) with pediatric intensive care unit (PICU) length of stay and mortality in critically ill pediatric patients. Methods Data from children aged 2 months–18 years were collected, and bioelectrical impedance was performed to obtain phase angle. Severity was evaluated by scoring the Pediatric Index of Mortality. Descriptive statistics were reported for nominal variables. Receiver operating characteristic curve was used to analyze the association of phase angle with 30‐day mortality and to find the best cutoff. Survival probabilities and PICU length of stay were estimated using the Kaplan‐Meier method. Results We evaluated 247 children with a median age of 4.8 years whose main cause of admission was sepsis. Survival curves showed higher survival in patients with phase angle >2.8° compared with patients with phase angle ≤2.8° (P < .0001). Kaplan‐Meier time‐to‐event analysis showed that children with lower phase angle values were more likely to remain in the PICU (hazard ratio, 1.84; P = .003). Lower survival was also observed in patients who presented mid–upper arm circumference values ≤5th percentile (P < .03). Conclusions Mid–upper arm circumference and phase angle were associated with mortality and morbidity in critically ill children, suggesting that these parameters may be useful not only for nutrition diagnosis and monitoring, but also as an additional indicator in estimating prognosis.

show abstract

Section: Discussionmentioning

confidence: 99%

Bioelectrical Impedance Phase Angle and Morbidity and Mortality in Critically Ill Children

et al. 2018

View full text Add to dashboard Cite

show abstract

“…In summary, several terms have been used to characterize the nutrition status of an individual, and a call for unanimity has been raised by different experts from nutrition societies . Nonetheless, there is no doubt that unintentional weight loss and decreased food intake, with disease, which may further affect nutrient absorption and utilization, lead to a decline in overall body function, placing the individual at risk of increased morbimortality . Thus, the importance of identifying risk factors for undernutrition (screening) and, when indicated, further assessing the nutrition status (assessment) is fundamental to the best holistic approach of any sick individual.…”

Section: Nutrition Statusmentioning

confidence: 99%

“…45 Nonetheless, there is no doubt that unintentional weight loss and decreased food intake, with disease, which may further affect nutrient absorption and utilization, lead to a decline in overall body function, placing the individual at risk of increased morbimortality. 1,[46][47][48][49] Thus, the importance of identifying risk factors for undernutrition (screening) and, when indicated, further assessing the nutrition status (assessment) is fundamental to the best holistic approach of any sick individual. The disease per se may lead to undernutrition, and undernutrition alone affects disease outcomes in a vicious circle.…”

Section: Nutrition Statusmentioning

confidence: 99%

Nutrition Screening vs Nutrition Assessment: What’s the Difference?

Correia

2017

Nut in Clin Prac

Self Cite

View full text Add to dashboard Cite

Screening and assessment imply different processes, with the former indicating risk factors for a deprived nutrition condition and the latter providing the nutrition diagnosis. Both should be routinely performed at hospital admission according to recommended guidelines; however, this is not the reality worldwide, and undernutrition remains highly prevalent in the hospital setting. Therefore, the objective of the current review is to delve into the principles leading to nutrition status deficiencies and how they should be addressed by screening and assessment. A critical appraisal for the reasons associated with the misunderstanding between screening and assessing is proposed without further discussing the many available screening tools while approaching some of the assessment instruments. (Nutr Clin Pract. 2018;33:62-72)

show abstract

“…The gender difference in malnutrition effects on mortality is due to the better (baseline) survival in non-malnutrition women than in men, including 95.8 days for women and 35.9 days for men for in-hospital survival, and 299.0 days for women and 268.0 days for men for 1-year survival. One study of malnutrition in patients with cancer reported that gender differences were possibly related to the role of nutritional status in survival 17. But additional larger studies may be required to further examine the gender differences of malnutrition on survival in critically ill patients with acute renal failure.…”

Section: Discussionmentioning

confidence: 99%

Nutritional Status Plays a Crucial Role in the Mortality of Critically Ill Patients with Acute Renal Failure

Zhang

Dong

2018

Journal of Investigative Medicine

View full text Add to dashboard Cite

We aimed to clarify associations between nutritional status and mortality in patients with acute renal failure. De-identified data were obtained from the Medical Information Mart for Intensive Care III database comprising more than 40,000 critical care patients treated at Beth Israel Deaconess Medical Centerbetween 2001 and 2012. Weight loss and body mass index criteria were used to define malnutrition. Data of 193 critically ill patients with acute renal failure were analyzed, including demographics, nutrition intervention, laboratory results, and disease severity. Main outcomes were in-hospital and 1-year mortality. The 1-year mortality was significantly higher in those with malnutrition than in those without malnutrition (50.0% vs 29.3%, p=0.010), but differences in in-hospital survival were not significant (p=0.255). Significant differences in mortality were found between those with malnutrition and without starting at the 52nd day after intensive care unit (ICU) discharge (p=0.036). No significant differences were found between men and women with malnutrition in in-hospital mortality (p=0.949) and 1-year mortality (p=0.051). Male patients requiring intervention with blood products/colloid supplements had greater risk of 1-year mortality, but without statistical significance. Nutritional status is a predictive factor for mortality among critically ill patients with acute renal failure, particularly 1-year mortality after ICU discharge.

show abstract

Nutritional Status Parameters as Risk Factors for Mortality in Cancer Patients

Cited by 22 publications

References 35 publications

Bioelectrical Impedance Phase Angle and Morbidity and Mortality in Critically Ill Children

Bioelectrical Impedance Phase Angle and Morbidity and Mortality in Critically Ill Children

Nutrition Screening vs Nutrition Assessment: What’s the Difference?

Nutritional Status Plays a Crucial Role in the Mortality of Critically Ill Patients with Acute Renal Failure

Contact Info

Product

Resources

About