Nutritional support and risk status among cancer patients in palliative home care services

Orrevall, Ylva; Tishelman, Carol; Permert, Johan; Cederholm, Tommy

doi:10.1007/s00520-008-0467-4

Cited by 38 publications

(37 citation statements)

References 33 publications

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“…Degree of weight loss was categorized into: 1) weight increased, stable or loss < 5%; 2) weight loss ≥ 5% to < 10%; or 3) weight loss ≥ 10%. These cut-offs were chosen based on previous research on malnutrition screening and assessment instruments [22,24]. Changes in food intake were dichotomized into having eaten “less than usual” versus having eaten “as usual or more”.…”

Section: Methodsmentioning

confidence: 99%

Self-reported taste and smell alterations in patients under investigation for lung cancer

et al. 2014

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This study of patients under investigation for lung cancer (LC) aims to: 1) examine the prevalence of self-reported taste and smell alterations (TSAs) and their relationships with demographic and clinical characteristics; and 2) explore nutritional importance of TSAs by examining their associations with patient-reported weight loss, symptoms interfering with food intake, and changes in food intake.MethodsPatients were recruited consecutively during investigation for LC from one university hospital in Sweden. Patient-reported information on TSAs, demographics, six-month weight history, symptoms interfering with food intake, and changes in food intake was obtained. Relationships between TSAs and other variables were examined using two-tailed significance tests. In addition, putative explanatory factors for weight loss were explored in those patients diagnosed with LC, since a relationship between TSAs and weight loss was found in this group.ResultsThe final sample consisted of 215 patients, of which 117 were diagnosed with primary LC within four months of study inclusion and 98 did not receive a cancer diagnosis. The 38% prevalence of TSAs was identical in both groups, and were generally reported as mild and not interfering with food intake. However, a statistically significant relationship between TSAs and weight loss was found among patients with LC, with a median weight change of − 5.5% and a higher frequency of weight loss ≥ 10%. Patients with LC and weight loss ≥ 10%, had higher frequency of reporting TSAs, of decreased food intake and of ≥ 1 symptom interfering with food intake compared with those with less weight loss.Conclusion TSAs, although relatively mild, were present in 38% of patients with and without LC. Relationships between TSAs and weight loss were found among patients with LC, but not fully explained by decreased food intake. This highlights the complexity of cancer-related weight loss.

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Section: Methodsmentioning

confidence: 99%

Self-reported taste and smell alterations in patients under investigation for lung cancer

et al. 2014

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“…However, for screening purposes, in routine clinical practice the SGA as well as anthropometric measurements beyond the BMI may be too complex and time-consuming, and serum surrogate parameters, while defining decreased hepatic protein synthesis due to protein-calorie malnutrition, may not be specific enough [5,19,50]. Thus, for screening purposes, the NRS has been established and proven to be a valid tool for identifying patients at high risk of malnutrition or actually malnourished [10,43,47,52,55,56]. These NEN patients should then be further investigated with other methods.…”

Section: Discussionmentioning

confidence: 99%

“…Other methods of assessing nutritional status have been the measurement of several circulating serum proteins such as albumin or transferrin as surrogates of protein turnover [5,50] or the combination of albumin with body weight as the Nutritional Risk Index (NRI) [24,51]. Ultimately, all these methods have proven valid in assessing malnutrition in the general population and in oncological patients in particular, and have been correlated with overall survival of the specific patient groups studied [5,6,7,10,17,18,20,47,52,53,54,55,56]. …”

Section: Introductionmentioning

confidence: 99%

Malnutrition Predicts Clinical Outcome in Patients with Neuroendocrine Neoplasia

et al. 2015

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Malnutrition is a common problem in oncological diseases, influencing treatment outcomes, treatment complications, quality of life and survival. The potential role of malnutrition has not yet been studied systematically in neuroendocrine neoplasms (NEN), which, due to their growing prevalence and additional therapeutic options, provide an increasing clinical challenge to diagnosis and management. The aim of this cross-sectional observational study, which included a long-term follow-up, was therefore to define the prevalence of malnutrition in 203 patients with NEN using various methodological approaches, and to analyse the short- and long-term outcome of malnourished patients. A detailed subgroup analysis was also performed to define risk factors for poorer outcome. When applying malnutrition screening scores, 21-25% of the NEN patients were at risk of or demonstrated manifest malnutrition. This was confirmed by anthropometric measurements, by determination of serum surrogate parameters such as albumin as well as by bioelectrical impedance analysis (BIA), particularly phase angle α. The length of hospital stay was significantly longer in malnourished NEN patients, while long-term overall survival was highly significantly reduced. Patients with high-grade (G3) neuroendocrine carcinomas, progressive disease and undergoing chemotherapy were at particular risk of malnutrition associated with a poorer outcome. Multivariate analysis confirmed the important and highly significant role of malnutrition as an independent prognostic factor for NEN besides proliferative capacity (G3 NEC). Malnutrition is therefore an underrecognized problem in NEN patients which should systematically be diagnosed by widely available standard methods such as Nutritional Risk Screening (NRS), serum albumin assessment and BIA, and treated to improve both short- and long-term outcomes.

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“…A high-protein, moderate-fat diet consumed in small, frequent meals can be benefit to improve tolerance to diet. What's more, nutritional therapy could be provided via orally intake, enteral feeding tubes or parenteral means (Orrevall et al, 2009).…”

Section: Determinants Of Weight Loss In Patients With Esophageal Carcmentioning

confidence: 99%

Clinical Determinants of Weight Loss in Patients with Esophageal Carcinoma During Radiotherapy: a Prospective Longitudinal View

Jiang

Jin-zhi²,

Chen³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Purpose: The prevalence of weight loss in esophageal carcinoma patients is high and associated with impairment of physical function, increased psychological distress and low quality of life. It is not known which factors may contribute to weight loss in patients with esophageal carcinoma during radiotherapy in China. The objective of this study was to identify the associated demographic and clinical factors influencing weight loss.

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Nutritional support and risk status among cancer patients in palliative home care services

Cited by 38 publications

References 33 publications

Self-reported taste and smell alterations in patients under investigation for lung cancer

Self-reported taste and smell alterations in patients under investigation for lung cancer

Malnutrition Predicts Clinical Outcome in Patients with Neuroendocrine Neoplasia

Clinical Determinants of Weight Loss in Patients with Esophageal Carcinoma During Radiotherapy: a Prospective Longitudinal View

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