Nutritional support in chronic obstructive pulmonary disease: a systematic review and meta-analysis

Collins, Peter; Stratton, Rebecca J.; Elia, Marinos

doi:10.3945/ajcn.111.023499

Cited by 148 publications

(132 citation statements)

References 58 publications

(140 reference statements)

Supporting

Mentioning

115

Contrasting

Unclassified

Order By: Relevance

“…29 The reduction in body weight and FFM in COPD patients is mainly ascribed to a disturbed energy balance, since it has been shown that these patients may exhibit an increased daily energy expenditure compared with healthy subjects. 30 It is not yet clear whether malnutrition in people with COPD is the cause of their deterioration or just part of the progress of the disease 31 ; in any case it may be only partially reversed by nutritional supplementation. 32 The results of this study are in line with those of previous reports showing that body weight depletion is related to a decreased exercise performance in COPD patients.…”

Section: Discussionmentioning

confidence: 99%

Fat-Free Mass Depletion Is Associated With Poor Exercise Capacity Irrespective of Dynamic Hyperinflation in COPD Patients

et al. 2013

View full text Add to dashboard Cite

BACKGROUND:In patients with COPD, we investigated the effect of the fat-free mass (FFM) on maximal exercise capacity and the relationship with changes in operational lung volumes during exercise. METHODS: In a cross-sectional study 57 patients (16 females; age 65 ؎ 8 y) were consecutively assessed by resting lung function, symptom-limited cardiopulmonary exercise test, and body composition by means of bioelectrical impedance analysis to measure the FFM index (FFMI; in kilograms per square meter). RESULTS: Patients were categorized as depleted (n ‫؍‬ 14) or nondepleted (n ‫؍‬ 43) according to FFMI. No significant difference in gender, age, and resting lung function was found between depleted and nondepleted patients. When compared with nondepleted COPD patients, the depleted COPD patients had a significantly lower O 2 uptake at the peak of exercise and at anaerobic threshold as well as at peak oxygen pulse, oxygen uptake efficiency slope (OUES), and heart rate recovery (HRR) (P < .05 for all comparisons), but similar inspiratory capacity/total lung capacity at the peak of exercise. Moreover, they also reported significantly higher leg fatigue (P < .05), but not dyspnea on exertion. In all patients, significant correlations (P < .01) were found between FFMI and peak oxygen pulse, OUES, HRR, and leg fatigue. CONCLUSIONS: This study shows that FFM depletion plays a part in the reduction of exercise capacity in COPD patients, regardless of dynamic hyperinflation, and is strictly associated with poor cardiovascular response to exercise and to leg fatigue, but not with dyspnea.

show abstract

Section: Discussionmentioning

confidence: 99%

Fat-Free Mass Depletion Is Associated With Poor Exercise Capacity Irrespective of Dynamic Hyperinflation in COPD Patients

et al. 2013

View full text Add to dashboard Cite

show abstract

“…COLLINS and co-workers [92,93] also published recent meta-analyses using different methods. They did not include all of the same papers, but their findings were broadly in line with the Cochrane review.…”

Section: Treatment Of Weight Loss In Copdmentioning

confidence: 99%

Nutritional assessment and therapy in COPD: a European Respiratory Society statement

et al. 2014

View full text Add to dashboard Cite

Nutrition and metabolism have been the topic of extensive scientific research in chronic obstructive pulmonary disease (COPD) but clinical awareness of the impact dietary habits, nutritional status and nutritional interventions may have on COPD incidence, progression and outcome is limited. A multidisciplinary Task Force was created by the European Respiratory Society to deliver a summary of the evidence and description of current practice in nutritional assessment and therapy in COPD, and to provide directions for future research. Task Force members conducted focused reviews of the literature on relevant topics, advised by a methodologist. It is well established that nutritional status, and in particular abnormal body composition, is an important independent determinant of COPD outcome. The Task Force identified different metabolic phenotypes of COPD as a basis for nutritional risk profile assessment that is useful in clinical trial design and patient counselling. Nutritional intervention is probably effective in undernourished patients and probably most when combined with an exercise programme. Providing evidence of costeffectiveness of nutritional intervention is required to support reimbursement and thus increase access to nutritional intervention. Overall, the evidence indicates that a well-balanced diet is beneficial to all COPD patients, not only for its potential pulmonary benefits, but also for its proven benefits in metabolic and cardiovascular risk. @ERSpublications Metabolism and nutrition: shifting paradigms in COPD management

show abstract

“…The relationship between obesity, the worsening of comorbidities and the symptom burden is poorly investigated [58]. Recent studies suggest that nutrition therapy may improve the condition of severely underweight patients, particularly in combination with a rehabilitation program [58–60]. …”

Section: Malnutritionmentioning

confidence: 99%

Danish respiratory society position paper: palliative care in patients with chronic progressive non-malignant lung diseases

Marsaa

Gundestrup

Lange

et al. 2018

European Clinical Respiratory Journal

View full text Add to dashboard Cite

Background: Chronic non-malignant lung diseases such as chronic obstructive pulmonary disease (COPD) and interstitial lung diseases (ILD) result in reduced quality of life (QoL), a high symptom burden and reduced survival. Patients with chronic non-malignant lung disease often have limited access to palliative care. The symptom burden and the QoL of these patients resembles patients with cancer and the general palliative approach is similar. However, the disease trajectory is often slow and unpredictable, and the palliative effort must be built on accessibility, continuity and professional competences. The Danish Health Authority as well as the WHO recommends that there is access to palliative care for all patients with life-threatening diseases regardless of diagnosis. In 2011, the Danish Health Authority requested that the national medical societies would to formulate guidelines for palliation. Methods: In 2015, a group of members of the Danish Respiratory Society (DRS) was appointed for this purpose. It was composed of experienced ILD and COPD researchers as well as clinicians from different parts of Denmark. A literature review was made, a draft was prepared, and all recommendations were agreed upon unanimously. Results: The Danish version of the position paper was finally submitted for review and accepted by all members of DRS. Conclusion: In this position paper we provide recommendations on the terminology of chronic and terminal lung failure, rehabilitation and palliative care, advanced care planning, informal caregivers and bereavement, symptom management, the imminently dying patient, and organization of palliative care for patients with chronic non-malignant lung diseases.

show abstract

Nutritional support in chronic obstructive pulmonary disease: a systematic review and meta-analysis

Cited by 148 publications

References 58 publications

Fat-Free Mass Depletion Is Associated With Poor Exercise Capacity Irrespective of Dynamic Hyperinflation in COPD Patients

Fat-Free Mass Depletion Is Associated With Poor Exercise Capacity Irrespective of Dynamic Hyperinflation in COPD Patients

Nutritional assessment and therapy in COPD: a European Respiratory Society statement

Danish respiratory society position paper: palliative care in patients with chronic progressive non-malignant lung diseases

Contact Info

Product

Resources

About