“…The plasma fatty acid concentrations were the primary outcomes of the present study. A power calculation based on the n-3 fatty acid profile resulting from the administration of a multicomponent emulsion in a previous study (19,20) showed that 8 infants per group were required to find a statistically significant difference, with an a of 0.05 and a power of 0.80 (assuming an increase in the plasma EPA and DHA concentrations of 1.8% with a standard deviation of 1.4%). Because this study was part of a larger trial (13) and to allow for the comparison of safety outcomes, 48 infants were included in each group.…”
The multicomponent lipid emulsion was well tolerated and associated with improved growth and higher plasma fatty acid profiles in VLBW infants in comparison with the pure soybean oil emulsion.
“…The plasma fatty acid concentrations were the primary outcomes of the present study. A power calculation based on the n-3 fatty acid profile resulting from the administration of a multicomponent emulsion in a previous study (19,20) showed that 8 infants per group were required to find a statistically significant difference, with an a of 0.05 and a power of 0.80 (assuming an increase in the plasma EPA and DHA concentrations of 1.8% with a standard deviation of 1.4%). Because this study was part of a larger trial (13) and to allow for the comparison of safety outcomes, 48 infants were included in each group.…”
The multicomponent lipid emulsion was well tolerated and associated with improved growth and higher plasma fatty acid profiles in VLBW infants in comparison with the pure soybean oil emulsion.
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