2024
DOI: 10.1002/adbi.202400218
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o8G‐miR‐6513‐5p/BCL2L13 Axis Regulates Mitophagy during Oxidative Stress in the Human Saphenous Vein Endothelial Cells

Hao Jia,
Le Kang,
Ben Huang
et al.

Abstract: Venous graft decay (VGD) occurs in coronary artery bypass grafting (CABG), and ischemia‐reperfusion oxidative stress injury during the operation is involved in VGD. To explore the cellular phenotypic changes during this process, a stable oxidative stress model of human saphenous vein endothelial cells (HSVECs) is constructed. Through proteomics and cell experiments, it is found that the expression of BCL2L13 is upregulated during oxidative stress of HSVECs, and BCL2L13 regulated mitophagy through receptor‐medi… Show more

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