Obesidad en escolares de Mérida, Venezuela: asociación con factores de riesgo cardiovascular

Paoli, Mariela; Uzcátegui, Lilia; Zerpa, Yajaira; Gómez‐Pérez, Roald; Camacho, Nolis; Molina, Zarela; Cichetti, Rosanna; Vallarroel, Vanessa; Fargier, A; Arata-Bellabarba, Gabriela

doi:10.1016/s1575-0922(09)71404-4

Cited by 19 publications

(7 citation statements)

References 39 publications

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“…Our study demonstrated an abnormal lipid profile with regard to elevated total cholesterol, triglycerides, LDL-C, and atherogenic index, and reduced HDL-C in overweight or obese children. Our results show that overweight and obesity in school children increases the likelihood of adverse cardiovascular risk factors, including increased waist circumference and hypercholesterolemia, hypertriglyceridemia, and low HDL-C, which is consistent with previous studies 34–36. Botton et al showed partial correlations between hypertriglyceridemia, hyperinsulinemia, and low plasma HDL-C levels that were related to all measures of adiposity in 452 children aged 8–17 years.…”

Section: Discussionsupporting

confidence: 93%

Association of lipid profile and waist circumference as cardiovascular risk factors for overweight and obesity among school children in Qatar

Rizk¹,

Yousef²

2012

DMSO

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BackgroundChildhood obesity is a national as well as worldwide problem. The aim of this study was to evaluate the association of overweight and obesity among Qatari children with lipid profile and waist circumference as adverse cardiovascular risk factors in children aged 6–11 years. International Obesity Task Force reference values were used to screen for overweight and obesity.MethodsA cross-sectional study in a randomly selected sample was conducted in 315 Qatari primary school students aged 6–11 years. Anthropometric measurements, including body weight, height, waist circumference, and body mass index were calculated for 151 girls and 164 boys. Weight categories were based on International Obesity Task Force reference values. Fasting blood glucose, total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides were measured, and atherogenic index was calculated.ResultsIn total, 31.71% of boys and 32.78% of girls were overweight or obese. Overweight and obese children screened against International Obesity Task Force reference values had a significantly increased risk of high waist circumference (P < 0.0001), hypertriglyceridemia (P = 0.002), low HDL-C (P = 0.017), and atherogenic index (P = 0.021) compared with children who were not overweight or obese. The partial correlation coefficient for the cardiovascular risk marker of waist circumference indicated a positive significant association with total cholesterol (r = 0.465, P = 0.003), triglycerides (r = 0.563, P < 0.001), and LDL-C (r = 0.267, P = 0.003), and a significant negative association with HDL-C (r = −0.361, P = 0.004). Overweight and obesity significantly increase the odds ratios (ORs) and 95% confidence interval (CIs) of cardiovascular risk factors as follows: hypertriglyceridemia (OR 6.34, CI 2.49–13.44, P < 0.0001); LDL-C (OR 3.18, CI 1.04–9.75, P = 0.043); hypercholesterolemia (OR 1.88, CI 1.10–3.19, P = 0.020); and increased waist circumference (OR 1.40, CI 1.29–1.55, P = 0.022). Overweight and obesity significantly increased the risk of atherosclerosis (assessed by atherogenic index) by about two-fold (OR 1.83, 95% CI 1.06–3.15, P = 0.025).ConclusionOverweight and obese children screened by International Obesity Task Force reference values are at increased risk of cardiovascular disease in adulthood.

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Section: Discussionsupporting

confidence: 93%

Association of lipid profile and waist circumference as cardiovascular risk factors for overweight and obesity among school children in Qatar

Rizk¹,

Yousef²

2012

DMSO

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“…Data obtained in a major city in the Venezuelan Andes seem to indicate a similar trend [4, 5]. Childhood obesity may lead to diabetes mellitus, cardiovascular disease, and premature death in adulthood [6].…”

Section: Introductionmentioning

confidence: 95%

Limited Weight Loss or Simply No Weight Gain following Lifestyle-Only Intervention Tends to Redistribute Body Fat, to Decrease Lipid Concentrations, and to Improve Parameters of Insulin Sensitivity in Obese Children

Marcano

Fernández

Paoli

et al. 2011

International Journal of Pediatric Endocrinology

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Objectives. To investigate whether lifestyle-only intervention in obese children who maintain or lose a modest amount of weight redistributes parameters of body composition and reverses metabolic abnormalities. Study Design. Clinical, anthropometric, and metabolic parameters were assessed in 111 overweight or obese children (CA of 11.3 ± 2.8 years; 63 females and 48 males), during 8 months of lifestyle intervention. Patients maintained or lost weight (1–5%) (group A; n: 72) or gained weight (group B). Results. Group A patients presented with a decrease in systolic blood pressure (SBP) and diastolic blood pressure (DBP) ( and , resp.), BMI (), z-score BMI (), waist circumference (), fat mass (), LDL-C (), Tg/HDL-C ratio (), fasting and postprandial insulin (), and HOMA (), while HDL-C () and QUICKI increased (). Conversely, group B patients had an increase in BMI (), waist circumference (), SBP (), and in QUICKI (), while fat mass (), fasting insulin (), and HOMA () decreased. Lean mass, DBP, lipid concentrations, fasting and postprandial glucose, postprandial insulin, and ultrasensitive C-reactive protein (CRP) remained stable. Conclusions. Obese children who maintain or lose a modest amount of weight following lifestyle-only intervention tend to redistribute their body fat, decrease blood pressure and lipid levels, and to improve parameters of insulin sensitivity.

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“…In Venezuela, in an evaluation of 370 children aged 7---9 years from the city of Merida, MS frequency was 0.4% in normal weight children and 38.9% in obese children. 20 Since differences in lifestyle and/or genetic determinants are responsible for variations in reference values between the different populations, 12,13 and because of the discrepancies in definition of MS in this age group, in which early diagnosis and intervention would hypothetically improve the quality of life of individuals at risk, a population study was conducted in children and adolescents from Municipio Libertador in Mérida-Venezuela to collect our own updated reference BP and blood lipid values and to establish the prevalence of MS using the most widely accepted classifications for this purpose and ascertain whether differences occur when local, instead of international, cut-off points are used for the different components.…”

Section: Introductionmentioning

confidence: 99%

Metabolic syndrome in children and adolescents from Mérida city, Venezuela: Comparison of results using local and international reference values (CREDEFAR study)

Reyes

Mederico

Valeri

et al. 2014

Endocrinología y Nutrición (English Edition)

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Obesidad en escolares de Mérida, Venezuela: asociación con factores de riesgo cardiovascular

Cited by 19 publications

References 39 publications

Association of lipid profile and waist circumference as cardiovascular risk factors for overweight and obesity among school children in Qatar

Association of lipid profile and waist circumference as cardiovascular risk factors for overweight and obesity among school children in Qatar

Limited Weight Loss or Simply No Weight Gain following Lifestyle-Only Intervention Tends to Redistribute Body Fat, to Decrease Lipid Concentrations, and to Improve Parameters of Insulin Sensitivity in Obese Children

Metabolic syndrome in children and adolescents from Mérida city, Venezuela: Comparison of results using local and international reference values (CREDEFAR study)

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