Obesidade canina e inflamação: estudo dos microRNAs envolvidos com a expressão de macrófagos no tecido adiposo

Abstract

parte dos requisitos para a obtenção do título de Mestre em Ciências.

Atividade física e marcadores de inflamação em pacientes com esquizofrenia

“…It was also reported a more pronounced increase, although not statistically significant, in the post-exercise TNF-α parameters among individuals with schizophrenia. 41 The inflammatory marker elevation found in the study group may suggest there is a lower correlation between fitness and a higher degree of inflammatory response, which is already stated in the literature. 40,41 Our studied population was considered physically unfit: they are chronic patients, mostly overweight (BMI > 25 kg/m²), with severe impairment, besides using medications that have side effects and being evaluated at a tertiary service outpatients clinic.…”

“…41 The inflammatory marker elevation found in the study group may suggest there is a lower correlation between fitness and a higher degree of inflammatory response, which is already stated in the literature. 40,41 Our studied population was considered physically unfit: they are chronic patients, mostly overweight (BMI > 25 kg/m²), with severe impairment, besides using medications that have side effects and being evaluated at a tertiary service outpatients clinic. In agreement with Potvin (2008), one hypothesis might be that physical activity without supervision would cause an exaggerated inflammatory response in this population.…”

“…34 Although the scarce literature, only one study found that physical exercise was associated with inflammatory markers among psychotic patients. 41 In that study, 23 patients with schizophrenia were matched with controls. The subjects were then submitted to physical activity and peripheral blood samples were collected after exercise for analysis of cytokines.…”

“…In agreement with Potvin (2008), one hypothesis might be that physical activity without supervision would cause an exaggerated inflammatory response in this population. 40,41 The ability of physical activity to reduce serum levels of inflammatory markers does not seem to apply to some groups of individuals. For example, in one study, Greiwe (2001) elderly subjects were evaluated in a training program for 12 weeks, after which it was not observed any reduction in TNF-α and IL-6.…”