Obesity and dyslipidemia

Howard, Barbara V.; Ruotolo, Giacomo; Robbins, David C.

doi:10.1016/s0889-8529(03)00073-2

Cited by 252 publications

(200 citation statements)

References 29 publications

Supporting

Mentioning

168

Contrasting

Unclassified

Order By: Relevance

“…In men and non-pregnant women, %SFA, BMI and smoking have been demonstrated to be positively related with TC and/or TG levels, whereas physical activity, %LA and alcohol intake were inversely related (Willett et al, 1983;Razay et al, 1992;Millen et al, 1996;Sonnenberg et al, 1996;Howard et al, 2003;Kelley et al, 2004;Daryani et al, 2005a).…”

Section: Discussionmentioning

confidence: 99%

Ethnic differences in maternal total cholesterol and triglyceride levels during pregnancy: the contribution of demographics, behavioural factors and clinical characteristics

et al. 2011

View full text Add to dashboard Cite

Background/Objectives: Lipid disturbances during pregnancy may lead to early onset of metabolic diseases in the offspring. However, there is little knowledge on ethnic differences in lipid levels during pregnancy. We evaluated ethnic differences in non-fasting total cholesterol (TC) and triglyceride (TG) levels during early gestation and the role of demographics, behavioural factors and clinical characteristics. Subjects/Methods: Non-diabetic pregnant women (N ¼ 3025) from the Amsterdam Born Children and their Development (ABCD) study. The studied ethnic groups were Dutch, Surinam-Hindustani, African-Caribbean, Turkish, Moroccan and Ghanaian. A multilingual questionnaire was used to gather information on maternal demographics, behavioural factors and clinical characteristics. Non-fasting TC, TG, percentage saturated fatty acid (%SFA) and percentage linoleic acid status (%LA) were assessed in blood samples collected at the first antenatal visit. Results: Ghanaian (À0.51 mmol/l), African-Caribbean (À0.19 mmol/l) and Moroccan (À0.15 mmol/l) women had significant lower TC levels compared with Dutch women. TG levels were lower in Ghanaian (log transformed À0.12 mmol/l) but significantly higher in Surinam-Hindustani (0.10 mmol/l) and Turkish women (0.07 mmol/l). Age, physical activity, pre-pregnancy body mass index (BMI), smoking, %SFA and %LA were independently related to TC and/or TG. However, only pre-pregnancy BMI could partly explain observed disparities. Furthermore, pre-pregnancy BMI had a relatively large effect on TG levels in Surinam-Hindustani and Turkish women. Conclusions: TC and TG levels differed between ethnic groups during early gestation. Only pre-pregnancy BMI partly explained the ethnic differences to a relevant degree. Reduction in BMI before pregnancy may improve lipid profile, especially in Surinam-Hindustani and Turkish women.

show abstract

Section: Discussionmentioning

confidence: 99%

Ethnic differences in maternal total cholesterol and triglyceride levels during pregnancy: the contribution of demographics, behavioural factors and clinical characteristics

et al. 2011

View full text Add to dashboard Cite

show abstract

“…Insulin resistance and Diabetes mellitus affect virtually every lipid and lipoprotein and, therefore, dyslipidemia is present in most diabetic patients 27,31,32 . Dyslipidemia is reflected by elevated levels of triglycerides, VLDL and LDL-cholesterol and lower HDL-cholesterol levels 33 . Although our results do not reflect comments in clinical studies, the Brazilian Society of Cardiology acknowledges that decreased HDL (isolated or in association with increased levels of LDL and/or triglycerides) characterizes the laboratory classification of dyslipidemia 34 .…”

Section: Discussionmentioning

confidence: 99%

Neonatally-induced diabetes: lipid profile outcomes and oxidative stress status in adult rats

Sinzato¹,

Lima²,

Campos³

et al. 2009

Rev. Assoc. Med. Bras.

View full text Add to dashboard Cite

0.05) in the n5-STZ animals when compared to control group. However n5-STZ animals showed a significant decreased HDL-cholesterol rate (p<0.05). CONCLUSION: This streptozotocin-induced diabetes model in rats caused hyperglycemia (120-360mg/dL), characterizing mild diabetes. This glycemic level led to HDL-lipoprotein alteration, which was not sufficient to impair antioxidant enzyme activities or determination of lipid peroxidation in adult life of rats. Further this experimental investigation contributed to the understanding of different results found in other models for mild/moderate diabetes induction in laboratory animals as well as to a better comprehension of the pathophysiological mechanisms of mild diabetes or hyperglycemia in humans.]]>

show abstract

“…A obesidade, doença caracterizada pelo excesso de gordura corporal, é comumente associada às hiperlipidemias, principalmente hipertrigliceridemia e decréscimo dos níveis plasmáticos de HDL. Esta associação, sem dúvida desempenha papel importante no desenvolvimento de aterosclerose e DCV em indivíduos obesos (Howard et al, 2003).…”

Section: Introductionunclassified

Levantamento etnobotânico de plantas utilizadas como anti-hiperlipidêmicas e anorexígenas pela população de Nova Xavantina-MT, Brasil

Silva¹,

Melo²,

Ribeiro³

et al. 2010

Rev. bras. farmacogn.

View full text Add to dashboard Cite

RESUMO:O presente trabalho verificou a utilização de plantas medicinais encontradas no Cerrado mato-grossense para o tratamento de hiperlipidemias e obesidade. Entrevistas com 180 pessoas acima de 50 anos foram realizadas em Nova Xavantina-MT. O questionário abordou nome popular, parte utilizada, forma de preparo e uso das espécies citadas, além de informações gerais sobre o uso de plantas. -Hil.). A folha foi a parte mais utilizada (46%) e o preparo das plantas ocorre principalmente por meio de infusão citado por 36,5% dos entrevistados. Apesar do uso popular destas plantas no combate as hiperlipidemias e obesidade, há necessidade de estudos fitoquímicos e farmacológicos que comprovem estas atividades, com vistas ao desenvolvimento de um fitoterápico.Unitermos: Levantamento etnobotânico, Nova Xavantina, plantas medicinais, anti-hiperlipidêmicas, anorexígenas, Cerrado.ABSTRACT: "Ethnobotanical survey of plants used as anti-hyperlipidemic and anorexigenic by the population of Nova Xavantina-MT, Brazil". This study checked the use of medicinal plants found in the Cerrado mato-grossense for the treatment of hyperlipidemia and obesity. Interviews with 180 people over 50 years were held in Nova Xavantina-MT. The questionnaire addressed popular name, part used, type of preparation and use of the species mentioned, beyond general information about the use of plants. The ten plants most cited were collected, identified and studied through a literature review. Most respondents (95.6%) said using medicinal plants regularly, while 71.5% of them inherited the knowledge of plants of parents and grandparents and 94.20% reported the use to advise youngsters. Furthermore, 93.6% attested that the plants are more effective than the drugs from pharmacy and 57% considered the strong effect of the same, i.e., they always solved health problems. Regarding adverse effects, 95.9% said they have never felt them after the use of plants. Of the respondents, 56.7% knew or had used medicinal plants in the treatment of hyperlipidemias and obesity, being cited 54 medicinal species belonging to 53 different genera and 38 families, with emphasis on Fabaceae (13%

show abstract

Obesity and dyslipidemia

Cited by 252 publications

References 29 publications

Ethnic differences in maternal total cholesterol and triglyceride levels during pregnancy: the contribution of demographics, behavioural factors and clinical characteristics

Ethnic differences in maternal total cholesterol and triglyceride levels during pregnancy: the contribution of demographics, behavioural factors and clinical characteristics

Neonatally-induced diabetes: lipid profile outcomes and oxidative stress status in adult rats

Levantamento etnobotânico de plantas utilizadas como anti-hiperlipidêmicas e anorexígenas pela população de Nova Xavantina-MT, Brasil

Contact Info

Product

Resources

About