Obesity and Inflammation: Epidemiology, Risk Factors, and Markers of Inflammation

Rodríguez-Hernández, Heriberto; Simental‐Mendía, Luis E.; Rodríguez-Ramírez, Gabriela; Reyes-Romero, Miguel Arturo

doi:10.1155/2013/678159

Cited by 380 publications

(309 citation statements)

References 186 publications

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“…This agrees with findings among overweight and obese individuals that display elevated levels of inflammation due to the release of cytokines from adipose tissue [35]. The addition of a quinoa extract rich in 20-hydroxyecdysone to the high fat diet reversed the expression of inflammatory cytokines to levels associated with a low fat diet.…”

Section: Effects On Weight Gainsupporting

confidence: 89%

Physiological Effects Associated with Quinoa Consumption and Implications for Research Involving Humans: a Review

Simnadis

Tapsell

Beck

2015

Plant Foods Hum Nutr

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Quinoa is a pseudo-grain consumed as a dietary staple in South America. In recent years, consumer demand for quinoa in the developed world has grown steadily. Its perceived health benefits have been cited as a driving force behind this trend, but there are very few human studies investigating the impact of quinoa consumption. The aim of this review was to identify physiological effects of quinoa consumption with potential for human health. A critical evaluation of animal model studies was conducted. The quality of identified studies was assessed using a methodological quality assessment tool and summative conclusions were drawn to guide the direction of future human research. The majority of studies were of fair quality. Purported physiological effects of quinoa consumption included decreased weight gain, improved lipid profile and improved capacity to respond to oxidative stress. These physiological effects were attributed to the presence of saponins, protein and 20-hydroxyecdysone in the quinoa seed. The implications of these findings are that human studies should investigate the impact of quinoa consumption on weight gain and lipid levels. The role of quinoa as an antioxidant is still unclear and requires further elucidation in animal models. Disciplines Medicine and Health Sciences | Social and Behavioral Sciences AbstractQuinoa is a pseudo-grain consumed as a dietary staple in South America. In recent years, consumer demand for quinoa in the developed world has grown steadily. Its perceived health benefits have been cited as a driving force behind this trend, but there are very few human studies investigating the impact of quinoa consumption.The aim of this review was to identify physiological effects of quinoa consumption with potential for human health. A critical evaluation of animal model studies was conducted. The quality of identified studies was assessed using a methodological quality assessment tool and summative conclusions were drawn to guide the direction of future human research. The majority of studies were of fair quality. Purported physiological effects of quinoa consumption included decreased weight gain, improved lipid profile and improved capacity to respond to oxidative stress. These physiological effects were attributed to the presence of saponins, protein and 20-2 hydroxyecdysone in the quinoa seed. The implications of these findings are that human studies should investigate the impact of quinoa consumption on weight gain and lipid levels. The role of quinoa as an antioxidant is still unclear and requires further elucidation in animal models.

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Section: Effects On Weight Gainsupporting

confidence: 89%

Physiological Effects Associated with Quinoa Consumption and Implications for Research Involving Humans: a Review

Simnadis

Tapsell

Beck

2015

Plant Foods Hum Nutr

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“…Our results indicated the inflammation development in rats with MSGinduced obesity. It should be noted that in the case of obesity, chronic low-grade inflammation, which comes out in increased levels of acutephase proteins and pro-inflammatory mediators in blood serum [18], plays a critical role in the development of cardiovascular dysfunction [19], insulin resistance and type II diabetes [7,20].…”

Section: Resultsmentioning

confidence: 99%

Probiotic strains of lactobacilli and bifidobacteria alter pro- and anti-inflammatory cytokines production in rats with monosodium glutamate-induced obesity

Falalyeyeva¹,

Leschenko²,

Берегова³

et al. 2017

Fiziol Zh

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The aim of this study was to investigate the effect of probiotic strains of Lactobacillus casei IMV B-7280, Bifidobacterium animalis VKL, B. animalis VKB on the pro-and anti-inflammatory cytokines production in Wistar male rats with monosodium glutamate (MSG)-induced obesity. It was established that neonatal administration of MSG to rats leads to increasing levels of the interleukin (IL)-1β and IL-12, and to decreasing of the IL-4, IL-10 and tumor growth factor (TGF)-β levels in the blood serum. After administration of the B. animalis VKL -B. animalis VKB -L. casei IMV B-7280 composition to obese rats the level of the IL-1β in blood serum wasn't differ from that in the obese rats, that didn't receive of the probiotic bacteria. But there was no statistically significant difference comparing with intact rats. The level of the IL-12B p40 in blood serum was decreased under influence of the B. animalis VKL -B. animalis VKB -L. casei IMV B-7280 composition (18.9 %, p < 0.05) and B. animalis VKL (10.5 %, p < 0.05) compared with obese rats, not receiving probiotic bacteria, but remained higher than in intact animals. After administration to obese rats of the B. animalis VKL -B. animalis VKB -L. casei IMV B-7280 composition the levels of the IL-4, IL-

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“…In recent years, it has been demonstrated that obesity is associated with chronic systemic inflammation, this status is conditioned by the innate immune system activation in adipose tissue that promotes an increase in the production and release of pro-inflammatory cytokines that contribute to the triggering of the systemic acute-phase response [5].…”

Section: Obesity and Inflammation:-mentioning

confidence: 99%

Relationship Between Obesity and Immune System a Review Article

el-Fetoh¹,

Aodh²,

Alanazi³

et al. 2016

IJAR

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Obesity and Inflammation: Epidemiology, Risk Factors, and Markers of Inflammation

Cited by 380 publications

References 186 publications

Physiological Effects Associated with Quinoa Consumption and Implications for Research Involving Humans: a Review

Physiological Effects Associated with Quinoa Consumption and Implications for Research Involving Humans: a Review

Probiotic strains of lactobacilli and bifidobacteria alter pro- and anti-inflammatory cytokines production in rats with monosodium glutamate-induced obesity

Relationship Between Obesity and Immune System a Review Article

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