Obesity and Multisite Pain in the Lower Limbs: Data from the Osteoarthritis Initiative

Vennu, Vishal; Alenazi, Aqeel M.; Abdulrahman, Tariq A.; Binnasser, Ahmad S.; Bindawas, Saad M.

doi:10.1155/2020/6263505

Cited by 11 publications

(6 citation statements)

References 35 publications

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“…Because of the limited sample size, we chose to employ this simplified method. However, we did choose to separately examine comorbidities that have been examined by or found to be associated with pain in previous studies ( 9 , 22 , 23 ). For example, Vennu et al found that obesity was associated with multisite pain in the lower extremities in a population with arthritis ( 22 ).…”

Section: Discussionmentioning

confidence: 99%

“…However, we did choose to separately examine comorbidities that have been examined by or found to be associated with pain in previous studies ( 9 , 22 , 23 ). For example, Vennu et al found that obesity was associated with multisite pain in the lower extremities in a population with arthritis ( 22 ). In terms of waist circumference, Costa et al ( 23 ) reported an adjusted odds ratio ( OR ) of 2.03 (1.57–2.63) for waist circumference and multisite chronic pain while adjusting for depression .…”

Section: Discussionmentioning

confidence: 99%

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Central Obesity Is Associated With an Increased Rate of Multisite Pain in Older Adults

Dimino

Teruya²,

Silverman³

et al. 2022

Front. Public Health

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ObjectiveCentral obesity has been associated with several adverse health events, but little research exists about the longitudinal effects of central obesity on multisite pain. The purpose of this study was to assess if central obesity, as measured by waist circumference measurement, was associated with an increased rate of having multisite pain among older adults aged 65 years and older.DesignThe National Health and Aging Trends Study is a longitudinal cohort study initiated in 2011 and intended to be representative of Medicare beneficiaries in the contiguous United States.MethodsThere were 7,145 community-dwelling participants included in this study. Data for this study were collected annually between 2011 and 2018. Researchers assessed if waist circumference risk level was associated with an increased rate ratio of multisite pain. Weighted data were used in a multivariable generalized estimating equation model that used a log link specified with a Poisson distribution.ResultsParticipants with high-risk waist circumferences (98 cm or greater for women and 109 cm or greater for men) had a 11% higher rate of multisite pain than those with low-risk waist circumferences [rate ratio (RR) 1.11, 95% CI: 1.07–1.15] adjusting for gender, age, race, education, probable major depression, arthritis, and multimorbidity count.ConclusionAs measured by waist circumference, central adiposity is associated with multisite pain in older adults. While more research is needed, reducing waist circumference may prove beneficial in reducing the burden of multisite pain.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Central Obesity Is Associated With an Increased Rate of Multisite Pain in Older Adults

Dimino

Teruya²,

Silverman³

et al. 2022

Front. Public Health

View full text Add to dashboard Cite

show abstract

“…The PHQ-9 has a score range of 0-27, with higher scores indicating more severe depression. Score can be interpreted as indicating either no/minimal (0-4), mild (5-9), moderate (10)(11)(12)(13)(14), moderately severe (15)(16)(17)(18)(19) or severe depression (20)(21)(22)(23)(24)(25)(26)(27). The PHQ-9 is a valid and reliable measure.…”

Section: Depressionmentioning

confidence: 99%

“… 10 Systematic reviews and cohort studies have found a strong association between overweight and obesity and an increased prevalence of musculoskeletal pain, including low back pain, 11 12 knee osteoarthritis (OA), 13 foot pain 14 and shoulder pain. 15 16 Obesity is also associated with an increased likelihood of multisite pain in the lower limbs 17 as well as headaches, abdominal and pelvic pain, and chronic widespread pain/fibromyalgia. 18…”

Section: Introductionmentioning

confidence: 99%

Multidimensional pain profiling in people living with obesity and attending weight management services: a protocol for a longitudinal cohort study

et al. 2022

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IntroductionPain is prevalent in people living with overweight and obesity. Obesity is associated with increased self-reported pain intensity and pain-related disability, reductions in physical functioning and poorer psychological well-being. People living with obesity tend to respond less well to pain treatments or management compared with people living without obesity. Mechanisms linking obesity and pain are complex and may include contributions from and interactions between physiological, behavioural, psychological, sociocultural, biomechanical and genetic factors. Our aim is to study the multidimensional pain profiles of people living with obesity, over time, in an attempt to better understand the relationship between obesity and pain.Methods and analysisThis longitudinal observational cohort study will recruit (n=216) people living with obesity and who are newly attending three weight management services in Ireland. Participants will complete questionnaires that assess their multidimensional biopsychosocial pain experience at baseline and at 3, 6, 12 and 18 months post-recruitment. Quantitative analyses will characterise the multidimensional pain experiences and trajectories of the cohort as a whole and in defined subgroups.Ethics and disseminationThe study protocol has been approved by the Ethics and Medical Research Committee of St Vincent’s Healthcare Group, Dublin, Ireland (reference no: RS21-059) and the University College Dublin Human Research Ethics Committee (reference no: LS-E-22-41-Hinwood-Smart). Findings will be disseminated through peer-reviewed journals, conference presentations, public and patient advocacy groups, and social media.Study registrationOpen Science Framework Registration DOI:https://doi.org/10.17605/OSF.IO/QCWUE.

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“…In relation to sites of reported pain in PwO, the most common include low back [12,13] knee [14], foot [15], and shoulder pain [16,17]. Additionally, obesity is associated with increased likelihood of multisite pain in the lower limbs [18] as well as headaches, abdominal, pelvic pain, and chronic widespread pain/fibromyalgia [11]. A Swedish obesity registry study reported a pain prevalence (pain in five body locations: neck, back, hip, knee and ankles) of 58% among men and 68% among women [19].…”

Section: Introductionmentioning

confidence: 99%

The experiences of people living with obesity and chronic pain: A Qualitative Evidence Synthesis (QES) protocol

Hinwood,

Casey,

Doody

et al. 2024

PLoS ONE

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Introduction There is a substantial and progressive association between chronic pain (CP) and living with overweight or obesity. The relationship between obesity and CP is intricate and complex, with obesity being associated with increased pain-related disability, pain intensity, reduction in physical functioning and poorer psychological well-being. A Qualitative Evidence Synthesis (QES) provides an opportunity to better understand and reveal key areas within the patient experience of these complex interactions to inform best practice and future intervention design. Aims The aim of this QES is to methodically and systematically review and synthesise the qualitative literature reporting on the personal experiences of people who are both living with obesity (PwO) and chronic pain. Methods The phenomenon of interest of this QES is the lived experiences of PwO and CP. The following research question was developed using a modified Population, Intervention, Comparison, Outcome and Study type (PICOS) framework: “What are the lived experiences of people living with obesity and chronic pain?”. One review author will conduct a systematic search based on keywords and Medical Subject Headings (MeSH) terms for finding relevant articles in five peer-review databases, from inception to the date of searching. Two review authors will independently apply inclusion and exclusion criteria and screen articles in a two-stage process. The methodological quality of included studies will be assessed using the Critical Appraisal Skills Programme (CASP) tool and data will be extracted using a customised template. We will undertake a thematic synthesis of qualitative data from included studies and report our findings narratively. Confidence in the findings will be assessed based on the Grading of Recommendations Assessment, Development and Evaluation Confidence in Evidence from Reviews of Qualitative Research (GRADE-CER-Qual) approach. Findings and dissemination This study will follow the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA) and Enhancing Transparency in Reporting the Synthesis of Qualitative Research (ENTREQ) guidelines. It is anticipated that the findings of the review will facilitate a deep and broad understanding of the complex interactions between CP and obesity and will help inform best practice and future intervention design. Findings will be disseminated through journals that undergo peer review, presentations at conferences, engagement with public and patient advocacy groups, and social media. Ethics and dissemination Ethical approval is not required to conduct this review. Trail registration PROSPERO registration number: CRD42023361391.

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Obesity and Multisite Pain in the Lower Limbs: Data from the Osteoarthritis Initiative

Cited by 11 publications

References 35 publications

Central Obesity Is Associated With an Increased Rate of Multisite Pain in Older Adults

Central Obesity Is Associated With an Increased Rate of Multisite Pain in Older Adults

Multidimensional pain profiling in people living with obesity and attending weight management services: a protocol for a longitudinal cohort study

The experiences of people living with obesity and chronic pain: A Qualitative Evidence Synthesis (QES) protocol

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